Volatile evolution of long noncoding RNA repertoires: mechanisms and biological implications

•lncRNAs show weak selective constraint, even when clearly functional.•Gain and loss of lncRNA genes occurs at very high pace during evolution.•lncRNAs mostly evolve de novo.•Bidirectional promoters and transposable elements (TEs) promote the birth of lncRNAs.•Genomes rich in TEs may have more compl...

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Bibliographic Details

Published in:	Trends in genetics Vol. 30; no. 10; pp. 439 - 452
Main Authors:	Kapusta, Aurélie, Feschotte, Cédric
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.10.2014
Subjects:	Animals DNA Transposable Elements Evolution, Molecular Exons Humans Medical Education Nucleic Acid Conformation RNA, Long Noncoding - chemistry RNA, Long Noncoding - metabolism Transcription, Genetic
ISSN:	0168-9525
Online Access:	Get full text
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