Multiplying the efficiency and impact of biofortification through metabolic engineering

Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencie...

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Bibliographic Details
Published in:Nature communications Vol. 11; no. 1; pp. 5203 - 10
Main Authors: Van Der Straeten, Dominique, Bhullar, Navreet K., De Steur, Hans, Gruissem, Wilhelm, MacKenzie, Donald, Pfeiffer, Wolfgang, Qaim, Matin, Slamet-Loedin, Inez, Strobbe, Simon, Tohme, Joe, Trijatmiko, Kurniawan Rudi, Vanderschuren, Hervé, Van Montagu, Marc, Zhang, Chunyi, Bouis, Howarth
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 15.10.2020
Nature Publishing Group
Nature Portfolio
Subjects:
42/41
42/44
631/449/447/2311
631/61/318
631/61/447/8
706/1143
Biofortification - methods
Biotechnologie
Biotechnology
Breeding
Crops, Agricultural - genetics
Developing Countries
Food Supply
Food, Fortified
Global Health
Humanities and Social Sciences
Humans
Life sciences
Malnutrition - prevention & control
Metabolic Engineering - methods
Micronutrients
Minerals
multidisciplinary
Oryza
Perspective
Plants - genetics
Plants, Genetically Modified
Policy Making
Provitamins
Science
Science (multidisciplinary)
Sciences du vivant
Sustainable Development - economics
Sustainable Development - trends
Sustainable Development/economics/trends
United Nations
Vitamins
ISSN:2041-1723, 2041-1723
Online Access:Get full text
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Summary:Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal. Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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scopus-id:2-s2.0-85092572072
ISSN:2041-1723
2041-1723
DOI:10.1038/s41467-020-19020-4