Genetic Characterization of Enterovirus A71 Circulating in Africa

We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochthonous EV-A that might contribu...

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Bibliographic Details
Published in:Emerging infectious diseases Vol. 24; no. 4; pp. 754 - 757
Main Authors: Fernandez-Garcia, Maria Dolores, Volle, Romain, Joffret, Marie-Line, Sadeuh-Mba, Serge Alain, Gouandjika-Vasilache, Ionela, Kebe, Ousmane, Wiley, Michael R., Majumdar, Manasi, Simon-Loriere, Etienne, Sakuntabhai, Anavaj, Palacios, Gustavo, Martin, Javier, Delpeyroux, Francis, Ndiaye, Kader, Bessaud, Maël
Format: Journal Article
Language:English
Published: United States U.S. National Center for Infectious Diseases 01.04.2018
Centers for Disease Control and Prevention
Subjects:
acute flaccid paralysis
Africa
Analysis
Dispatch
enterovirus
Enterovirus A, Human - classification
Enterovirus A, Human - genetics
enterovirus A71
Enterovirus Infections - epidemiology
Enterovirus Infections - virology
Genetic aspects
Genetic Variation
Genetics
Genome, Viral
Genomics
Genotype
Human health and pathology
Humans
Infectious diseases
Life Sciences
Nervous system diseases
Paralysis
phylogenetic analysis
Phylogeny
recombination
Recombination, Genetic
Santé publique et épidémiologie
acute flaccid paralysis
phylogenetic analysis
viruses
recombination
enterovirus
Africa
enterovirus A71
whole-genome analysis
ISSN:1080-6040, 1080-6059, 1080-6059
Online Access:Get full text
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Summary:We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochthonous EV-A that might contribute to the emergence of pathogenic lineages.
Bibliography:ObjectType-Article-1
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ISSN:1080-6040
1080-6059
1080-6059
DOI:10.3201/eid2404.171783