Genetic Characterization of Enterovirus A71 Circulating in Africa
We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochthonous EV-A that might contribu...
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| Published in: | Emerging infectious diseases Vol. 24; no. 4; pp. 754 - 757 |
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| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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United States
U.S. National Center for Infectious Diseases
01.04.2018
Centers for Disease Control and Prevention |
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| ISSN: | 1080-6040, 1080-6059, 1080-6059 |
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| Abstract | We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochthonous EV-A that might contribute to the emergence of pathogenic lineages. |
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| AbstractList | We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of geno-group C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochtho-nous EV-A that might contribute to the emergence of patho-genic lineages. We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochthonous EV-A that might contribute to the emergence of pathogenic lineages.We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochthonous EV-A that might contribute to the emergence of pathogenic lineages. We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochthonous EV-A that might contribute to the emergence of pathogenic lineages. |
| Audience | Professional Academic |
| Author | Joffret, Marie-Line Kebe, Ousmane Sadeuh-Mba, Serge Alain Martin, Javier Bessaud, Maël Volle, Romain Wiley, Michael R. Ndiaye, Kader Majumdar, Manasi Gouandjika-Vasilache, Ionela Delpeyroux, Francis Simon-Loriere, Etienne Sakuntabhai, Anavaj Fernandez-Garcia, Maria Dolores Palacios, Gustavo |
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| Keywords | acute flaccid paralysis phylogenetic analysis viruses recombination enterovirus Africa enterovirus A71 whole-genome analysis |
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| Snippet | We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of genogroup C and the new genogroup E in West Africa.... We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of geno-group C and the new genogroup E in West Africa.... |
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| SubjectTerms | acute flaccid paralysis Africa Analysis Dispatch enterovirus Enterovirus A, Human - classification Enterovirus A, Human - genetics enterovirus A71 Enterovirus Infections - epidemiology Enterovirus Infections - virology Genetic aspects Genetic Variation Genetics Genome, Viral Genomics Genotype Human health and pathology Humans Infectious diseases Life Sciences Nervous system diseases Paralysis phylogenetic analysis Phylogeny recombination Recombination, Genetic Santé publique et épidémiologie |
| Title | Genetic Characterization of Enterovirus A71 Circulating in Africa |
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