Cellular changes in the postmortem hippocampus in major depression

Imaging studies report that hippocampal volume is decreased in major depressive disorder (MDD). A cellular basis for reduced hippocampal volume in MDD has not been identified. Sections of right hippocampus were collected in 19 subjects with MDD and 21 normal control subjects. The density of pyramida...

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Bibliographic Details
Published in:	Biological psychiatry (1969) Vol. 56; no. 9; pp. 640 - 650
Main Authors:	Stockmeier, Craig A., Mahajan, Gouri J., Konick, Lisa C., Overholser, James C., Jurjus, George J., Meltzer, Herbert Y., Uylings, Harry B.M., Friedman, Lee, Rajkowska, Grazyna
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 01.11.2004 Elsevier Science
Subjects:	Adult Adult and adolescent clinical studies Aged Aged, 80 and over Anatomy Biological and medical sciences Case-Control Studies Cell Count - methods Cell Size Central nervous system Depression Depressive Disorder, Major - pathology Female Fundamental and applied biological sciences. Psychology glia hippocampus Hippocampus - pathology Humans Imaging, Three-Dimensional - methods Male Medical sciences Middle Aged Mood disorders Neuroglia - pathology Neurons - pathology Postmortem Changes Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry pyramidal neurons Staining and Labeling - methods Time Factors Vertebrates: nervous system and sense organs pyramidal neurons Depression hippocampus glia Mood disorder Human Healthy subject Granule neuron Central nervous system Postmortem Pyramidal neuron Comparative study Hippocampus Encephalon Cell density
ISSN:	0006-3223, 1873-2402
Online Access:	Get full text
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