Biodistribution and radiation dosimetry of the positron emission tomography probe for AMPA receptor, [11C]K-2, in healthy human subjects

[ 11 C]K-2, a radiotracer exhibiting high affinity and selectivity for α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs), is suitable for the quantification of AMPARs in living human brains and potentially useful in the identification of epileptogenic foci in patients. This st...

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Bibliographic Details
Published in:	Scientific reports Vol. 11; no. 1; pp. 1598 - 10
Main Authors:	Hatano, Mai, Miyazaki, Tomoyuki, Ishiwata, Yoshinobu, Nakajima, Waki, Arisawa, Tetsu, Kuroki, Yoko, Kobayashi, Ayako, Takada, Yuuki, Ogawa, Matsuyoshi, Kawamura, Kazunori, Zhang, Ming-Rong, Higuchi, Makoto, Taguri, Masataka, Kimura, Yasuyuki, Takahashi, Takuya
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 15.01.2021 Nature Publishing Group Nature Portfolio
Subjects:	631/378/2586 692/53/2421 Dosimetry Human subjects Humanities and Social Sciences Injection Liver multidisciplinary Positron emission tomography Propionic acid Radiation dosimetry Radioactive tracers Science Science (multidisciplinary) Tomography Urinary bladder α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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