Targeting IL-4 for the Treatment of Atopic Dermatitis

Atopic dermatitis (AD) is an immune-mediated inflammatory skin disease characterized by a predominant type 2 immune response. Type 2 immunity is driven by multiple cytokines, including interleukin (IL)-4 and IL-13 that are considered central to AD pathogenesis and key therapeutic targets. The dual i...

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Veröffentlicht in:	ImmunoTargets and therapy Jg. 9; S. 151 - 156
Hauptverfasser:	Chiricozzi, Andrea, Maurelli, Martina, Peris, Ketty, Girolomoni, Giampiero
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Macclesfield Dove Medical Press Limited 01.01.2020 Taylor & Francis Ltd Dove Dove Medical Press
Schlagworte:	Advertising executives Atopic dermatitis B cells Cytokines Dendritic cells Dermatitis Dupilumab Eczema Gene expression Granulocytes il-4 il-4 inhibitor Immune response Immunotherapy Inflammation Interleukin 13 Interleukin 4 Interleukins Kinases Lymphocytes Monoclonal antibodies Neurons pascolizumab Pathogenesis pitrakinra Review Skin Skin diseases
ISSN:	2253-1556, 2253-1556
Online-Zugang:	Volltext
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