Innovations in HIV-1 Vaccine Design

The field of HIV-1 vaccinology has evolved during the last 30 years from the first viral vector HIV gene insert constructs to vaccination regimens using a myriad of strategies. These strategies now include germline-targeting, lineage-based, and structure-guided immunogen design. This narrative revie...

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Bibliographic Details
Published in:	Clinical therapeutics Vol. 42; no. 3; pp. 499 - 514
Main Authors:	Jones, Letitia D., Moody, M. Anthony, Thompson, Amelia B.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.03.2020 Elsevier Limited
Subjects:	Acquired immune deficiency syndrome AIDS AIDS Vaccines Animal models Animals Antibodies Binding sites bNAb Clinical trials Clinical Trials as Topic Design HIV HIV Infections - immunology HIV Infections - prevention & control HIV Infections - virology HIV vaccine Human immunodeficiency virus Humans immune correlates Immune system immunogen Infections Innovations Internal Medicine Medical research mRNA mRNA vaccines Nanoparticles Peptides Proteins Trimers Vaccination Vaccines Viruses bNAb immunogen immune correlates HIV vaccine
ISSN:	0149-2918, 1879-114X, 1879-114X
Online Access:	Get full text
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