Guards of the great wall: bacterial lysozyme inhibitors

Peptidoglycan is the major structural component of the bacterial cell wall. It provides resistance against turgor and its cleavage by hydrolases such as lysozymes results in bacteriolysis. Most, if not all, animals produce lysozymes as key effectors of their innate immune system. Recently, highly sp...

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Veröffentlicht in:	Trends in microbiology (Regular ed.) Jg. 20; H. 10; S. 501 - 510
Hauptverfasser:	Callewaert, Lien, Van Herreweghe, Joris M., Vanderkelen, Lise, Leysen, Seppe, Voet, Arnout, Michiels, Chris W.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.10.2012
Schlagworte:	Animals autolysin inhibition Bacteria Bacteria - enzymology Bacteria - metabolism bacterial lysozyme inhibitors Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism bacteria–host interaction cell walls Enzyme Inhibitors - chemistry Enzyme Inhibitors - metabolism Humans innate immunity Internal Medicine lysozyme Models, Biological Models, Molecular Muramidase - antagonists & inhibitors peptidoglycan peptidoglycans Phylogeny Sequence Homology turgor peptidoglycan autolysin inhibition bacterial lysozyme inhibitors bacteria–host interaction
ISSN:	0966-842X, 1878-4380, 1878-4380
Online-Zugang:	Volltext
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