Genomic patterns of homozygosity in worldwide human populations

Genome-wide patterns of homozygosity runs and their variation across individuals provide a valuable and often untapped resource for studying human genetic diversity and evolutionary history. Using genotype data at 577,489 autosomal SNPs, we employed a likelihood-based approach to identify runs of ho...

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Veröffentlicht in:	American journal of human genetics Jg. 91; H. 2; S. 275
Hauptverfasser:	Pemberton, Trevor J, Absher, Devin, Feldman, Marcus W, Myers, Richard M, Rosenberg, Noah A, Li, Jun Z
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 10.08.2012
Schlagworte:	Algorithms Chromosome Mapping - methods Cluster Analysis Genes, Recessive - genetics Genetic Variation Genome, Human - genetics Genomics - methods Genotype Geography Homozygote Humans Likelihood Functions Models, Genetic Polymorphism, Single Nucleotide - genetics
ISSN:	1537-6605, 1537-6605
Online-Zugang:	Weitere Angaben
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