The innate immune system in demyelinating disease

Demyelinating diseases such as multiple sclerosis are chronic inflammatory autoimmune diseases with a heterogeneous clinical presentation and course. Both the adaptive and the innate immune systems have been suggested to contribute to their pathogenesis and recovery. In this review, we discuss the r...

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Veröffentlicht in:	Immunological reviews Jg. 248; H. 1; S. 170 - 187
Hauptverfasser:	Mayo, Lior, Quintana, Francisco J., Weiner, Howard L.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Oxford, UK Blackwell Publishing Ltd 01.07.2012
Schlagworte:	Adaptive Immunity Animals astrocyte Astrocytes Astrocytes - immunology Astrocytes - metabolism Autoimmune diseases B-Lymphocytes - immunology B-Lymphocytes - metabolism Blood-Brain Barrier - immunology Blood-Brain Barrier - metabolism central nervous system Demyelinating diseases Demyelinating Diseases - immunology Demyelinating Diseases - metabolism Demyelination Dendritic cells Humans Immune system Immunity, Innate Inflammation Inflammatory diseases innate immunity Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Lymphocytes T Mast cells Mast Cells - immunology Mast Cells - metabolism Microglial cells Mononuclear Phagocyte System - immunology Mononuclear Phagocyte System - metabolism Multiple sclerosis Natural killer cells Reviews T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism
ISSN:	0105-2896, 1600-065X, 1600-065X
Online-Zugang:	Volltext
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