Diabetic retinopathy

Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complicati...

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Veröffentlicht in:	The Lancet (British edition) Jg. 376; H. 9735; S. 124 - 136
Hauptverfasser:	Cheung, Ning, Mitchell, Paul, Wong, Tien Yin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Kidlington Elsevier Ltd 10.07.2010 Elsevier Elsevier Limited
Schlagworte:	Angiogenesis Biological and medical sciences Blindness Blood pressure Cardiovascular diseases Clinical trials Coronary heart disease Diabetes Diabetes mellitus Diabetes. Impaired glucose tolerance Diabetic retinopathy Diabetic Retinopathy - diagnosis Diabetic Retinopathy - physiopathology Diabetic Retinopathy - therapy Edema Endocrine pancreas. Apud cells (diseases) Endocrinopathies Epidemiology Etiopathogenesis. Screening. Investigations. Target tissue resistance General aspects Glucose Heart diseases Humans Hypothyroidism Industrialized nations Internal Medicine Lasers Lipids Medical sciences Microvasculature Older people Ophthalmology Pregnancy Preservation Retina Retinopathies Retinopathy Risk Factors Rural areas Steroid hormones Stroke Studies Surgery Endocrinopathy Medicine Eye disease Retinopathy Diabetes mellitus
ISSN:	0140-6736, 1474-547X, 1474-547X
Online-Zugang:	Volltext
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Abstract	Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure. Optimum control of blood glucose, blood pressure, and possibly blood lipids remains the foundation for reduction of risk of retinopathy development and progression. Timely laser therapy is effective for preservation of sight in proliferative retinopathy and macular oedema, but its ability to reverse visual loss is poor. Vitrectomy surgery might occasionally be needed for advanced retinopathy. New therapies, such as intraocular injection of steroids and antivascular endothelial growth-factor agents, are less destructive to the retina than are older therapies, and could be useful in patients who respond poorly to conventional therapy. The outlook for future treatment modalities, such as inhibition of other angiogenic factors, regenerative therapy, and topical therapy, is promising.
AbstractList	Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure. Optimum control of blood glucose, blood pressure, and possibly blood lipids remains the foundation for reduction of risk of retinopathy development and progression. Timely laser therapy is effective for preservation of sight in proliferative retinopathy and macular oedema, but its ability to reverse visual loss is poor. Vitrectomy surgery might occasionally be needed for advanced retinopathy. New therapies, such as intraocular injection of steroids and antivascular endothelial growth-factor agents, are less destructive to the retina than are older therapies, and could be useful in patients who respond poorly to conventional therapy. The outlook for future treatment modalities, such as inhibition of other angiogenic factors, regenerative therapy, and topical therapy, is promising. Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure. Optimum control of blood glucose, blood pressure, and possibly blood lipids remains the foundation for reduction of risk of retinopathy development and progression. Timely laser therapy is effective for preservation of sight in proliferative retinopathy and macular oedema, but its ability to reverse visual loss is poor. Vitrectomy surgery might occasionally be needed for advanced retinopathy. New therapies, such as intraocular injection of steroids and antivascular endothelial growth-factor agents, are less destructive to the retina than are older therapies, and could be useful in patients who respond poorly to conventional therapy. The outlook for future treatment modalities, such as inhibition of other angiogenic factors, regenerative therapy, and topical therapy, is promising. [PUBLICATION ABSTRACT] Summary Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure. Optimum control of blood glucose, blood pressure, and possibly blood lipids remains the foundation for reduction of risk of retinopathy development and progression. Timely laser therapy is effective for preservation of sight in proliferative retinopathy and macular oedema, but its ability to reverse visual loss is poor. Vitrectomy surgery might occasionally be needed for advanced retinopathy. New therapies, such as intraocular injection of steroids and antivascular endothelial growth-factor agents, are less destructive to the retina than are older therapies, and could be useful in patients who respond poorly to conventional therapy. The outlook for future treatment modalities, such as inhibition of other angiogenic factors, regenerative therapy, and topical therapy, is promising. Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure. Optimum control of blood glucose, blood pressure, and possibly blood lipids remains the foundation for reduction of risk of retinopathy development and progression. Timely laser therapy is effective for preservation of sight in proliferative retinopathy and macular oedema, but its ability to reverse visual loss is poor. Vitrectomy surgery might occasionally be needed for advanced retinopathy. New therapies, such as intraocular injection of steroids and antivascular endothelial growth-factor agents, are less destructive to the retina than are older therapies, and could be useful in patients who respond poorly to conventional therapy. The outlook for future treatment modalities, such as inhibition of other angiogenic factors, regenerative therapy, and topical therapy, is promising.Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged people. It is identified in a third of people with diabetes and associated with increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure. Optimum control of blood glucose, blood pressure, and possibly blood lipids remains the foundation for reduction of risk of retinopathy development and progression. Timely laser therapy is effective for preservation of sight in proliferative retinopathy and macular oedema, but its ability to reverse visual loss is poor. Vitrectomy surgery might occasionally be needed for advanced retinopathy. New therapies, such as intraocular injection of steroids and antivascular endothelial growth-factor agents, are less destructive to the retina than are older therapies, and could be useful in patients who respond poorly to conventional therapy. The outlook for future treatment modalities, such as inhibition of other angiogenic factors, regenerative therapy, and topical therapy, is promising.
Author	Cheung, Ning Mitchell, Paul Wong, Tien Yin
Author_xml	– sequence: 1 givenname: Ning surname: Cheung fullname: Cheung, Ning organization: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia – sequence: 2 givenname: Paul surname: Mitchell fullname: Mitchell, Paul organization: Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Sydney, Australia – sequence: 3 givenname: Tien Yin surname: Wong fullname: Wong, Tien Yin email: ophwty@nus.edu.sg organization: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia
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Cites_doi	10.2337/dc07-0264 10.1001/archopht.122.4.546 10.1161/01.STR.0000254547.91276.50 10.1001/jama.298.8.902 10.1016/j.pharmthera.2009.03.010 10.1056/NEJMe058142 10.1016/j.ophtha.2009.03.003 10.1016/j.ophtha.2009.05.024 10.1016/j.ophtha.2004.02.004 10.1001/archophthalmol.2008.610 10.1016/S0140-6736(08)61411-7 10.1038/35008121 10.1016/S0140-6736(09)60750-9 10.1056/NEJMoa0802987 10.1001/archophthalmol.2009.172 10.1016/S0140-6736(08)61412-9 10.1167/iovs.05-0019 10.1136/bmj.b441 10.1001/archopht.126.6.793 10.1016/j.ophtha.2008.08.023 10.2337/dc09-1784 10.1016/j.jcrs.2008.09.019 10.1038/eye.2008.362 10.1016/S0140-6736(08)61413-0 10.1002/jcp.21426 10.1002/14651858.CD005656.pub2 10.2337/diacare.26.9.2653 10.1001/archophthalmol.2009.274 10.1167/iovs.05-1539 10.1136/bmj.a918 10.2337/dc08-1422 10.2337/db05-1635 10.1056/NEJMoa0802743 10.1056/NEJMoa0706245 10.2337/diacare.25.11.1919 10.2337/dc07-2075 10.1016/j.ophtha.2008.10.016 10.1016/S0140-6736(07)61104-0 10.1038/eye.2009.108 10.1167/iovs.07-0721 10.1370/afm.857 10.1038/nm1534 10.1016/j.survophthal.2006.12.003 10.1358/dot.2009.045.004.1354195 10.1080/10739680601072123 10.1016/S0161-6420(81)34978-1 10.1016/j.preteyeres.2007.07.005 10.1016/S0161-6420(95)31052-4 10.2337/diacare.13.10.1034 10.1016/j.ophtha.2009.02.002 10.1007/s00125-007-0822-x 10.1016/j.ophtha.2009.10.040 10.1016/j.ophtha.2008.09.023 10.1016/j.survophthal.2008.06.003 10.1016/S0140-6736(08)60343-8 10.2337/dc08-0189 10.1056/NEJMoa0808400 10.1007/s00417-008-0980-7 10.2337/diacare.27.10.2540 10.1001/archopht.122.1.76 10.1007/s00417-008-0884-6 10.1016/j.ophtha.2006.03.028 10.1056/NEJM199412013312203 10.2337/diabetes.50.2.444 10.1167/iovs.08-2521 10.2337/diacare.26.4.1224 10.2337/dc09-0102 10.2337/diacare.28.9.2252 10.1056/NEJMcibr0804551 10.2337/dc07-0332 10.1001/archopht.124.1.87 10.1001/archopht.126.12.1740 10.1097/00006982-200605000-00011 10.2337/dc09-0075 10.1016/j.ophtha.2009.01.014 10.1136/bjo.2005.083733 10.1001/jama.290.15.2057 10.1016/j.ajo.2005.08.063 10.1016/j.ophtha.2009.03.012 10.1097/IIO.0b013e31819fd5d7 10.2337/dc08-1233 10.2337/dc08-0342 10.1001/archophthalmol.2009.310 10.2337/dc07-1572 10.1016/0140-6736(91)92726-I 10.1038/nm0207-131 10.1136/bjo.2004.058347 10.1016/S0140-6736(07)61303-8 10.1056/NEJMcibr022629 10.2337/diacare.13.1.34 10.1001/archopht.122.4.552 10.1016/S0140-6736(03)12267-2 10.1056/NEJM200002103420603 10.1016/j.ophtha.2008.05.014 10.2337/db09-0059 10.2337/diacare.23.8.1084 10.1016/j.preteyeres.2008.09.002 10.1016/j.ajo.2008.08.024 10.1001/archopht.126.11.1548 10.1016/S1056-8727(03)00073-4 10.1517/14728210802584035 10.4158/EP.12.S1.34 10.2337/db09-1216 10.1016/j.ophtha.2008.10.003 10.1167/iovs.08-2473 10.1167/iovs.02-0648 10.1016/j.ophtha.2006.08.053 10.1001/archopht.1995.01100090070025 10.2337/dc07-1528 10.1016/j.ophtha.2008.06.015 10.1001/archopht.1985.01050110038020 10.2337/dc07-1657 10.2337/dc07-1622 10.1016/j.preteyeres.2007.12.001 10.1159/000075627 10.1056/NEJMoa041773 10.1001/archopht.116.7.874 10.1056/NEJMoa0808431 10.1001/jama.2009.726 10.2337/diab.46.11.1829 10.1016/j.jacc.2007.11.076 10.1016/S0161-6420(03)00475-5 10.1016/j.ophtha.2006.07.032 10.1016/j.preteyeres.2009.06.001 10.2337/diabetes.54.11.3103 10.1080/02713680903050592 10.7326/0003-4819-144-7-200604040-00005 10.1016/S0140-6736(97)06209-0 10.1001/archopht.126.12.1707 10.1056/NEJMoa0806359 10.1016/j.ophtha.2008.09.010 10.1016/S0161-6420(13)38011-7 10.1016/S0161-6420(88)33015-0 10.1016/j.ophtha.2007.07.010 10.2337/dc07-0927 10.1016/S0140-6736(07)61607-9 10.1016/S0140-6736(08)60333-5 10.1001/archopht.125.3.318
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Copyright	2010 Elsevier Ltd Elsevier Ltd 2015 INIST-CNRS Copyright 2010 Elsevier Ltd. All rights reserved. Copyright Elsevier Limited Jul 10-Jul 16, 2010 Copyright 2010 Elsevier Ltd. All rights reserved.
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Keywords	Endocrinopathy Medicine Eye disease Retinopathy Diabetes mellitus
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References	Kim, Equi, Bressler (bib133) 2007; 114 Wong, Loon, Saw (bib24) 2006; 90 White, Sun, Cleary (bib102) 2010; 59 Jeganathan, Wang, Wong (bib3) 2008; 31 Wong, Cheung, Tay (bib14) 2008; 115 Maia, Takahashi, Costa, Scott, Takahashi (bib143) 2009; 147 Klein, Klein, Moss, Wong, Sharrett (bib79) 2006; 113 (bib99) 2000; 23 Nguyen, Wang, Sharrett (bib78) 2008; 31 Takamura, Kubo, Akagi (bib137) 2009; 116 Wong, Liew, Mitchell (bib139) 2007; 370 Cheung, Wong (bib6) 2008; 27 Klein, Knudtson, Lee, Gangnon, Klein (bib20) 2008; 115 Grover, Li, Chong (bib53) 2008 Holman, Paul, Bethel, Neil, Matthews (bib112) 2008; 359 Wong, Islam, Klein (bib85) 2006; 47 Chan, Malik, Jia (bib23) 2009; 301 Liew, Klein, Wong (bib31) 2009; 49 Aiello, Avery, Arrigg (bib52) 1994; 331 Congdon, Friedman, Lietman (bib1) 2003; 290 Olsen, Sjolie, Hougaard (bib36) 2004; 18 Cheung, Wang, Klein, Couper, Richey Sharrett, Wong (bib46) 2007; 30 Scheppke, Aguilar, Gariano (bib147) 2008; 118 Williams, Scott, Haller, Maguire, Marcus, McDonald (bib95) 2004; 111 Wong, Liew, Tapp (bib103) 2008; 371 Chen, Connor, Aderman, Willett, Aspegren, Smith (bib67) 2009; 50 Hong, Mitchell, de Loryn, Rochtchina, Cugati, Wang (bib136) 2009; 116 Klein, Klein, Moss, Cruickshanks (bib27) 1995; 102 Farley, Mandava, Prall, Carsky (bib96) 2008; 6 Gaede, Lund-Andersen, Parving, Pedersen (bib122) 2008; 358 Garcia-Ramirez, Hernandez, Simo (bib68) 2008; 31 Mohamed, Gillies, Wong (bib7) 2007; 298 Ryan, Han, Ramsay (bib128) 2006; 26 (bib92) 1995; 113 Ginsburg, Aiello (bib89) 1993; XI Gerstein, Miller, Byington (bib105) 2008; 358 Tikellis, Wang, Tapp (bib80) 2007; 50 (bib90) 1991; 98 Beck, Edwards, Aiello (bib142) 2009; 127 Klein, Lee, Knudtson, Gangnon, Klein (bib19) 2009; 116 Carrasco, Hernandez, Miralles, Huguet, Farres, Simo (bib11) 2007; 30 Curtis, Gardiner, Stitt (bib48) 2009; 23 Keech, Mitchell, Summanen (bib120) 2007; 370 Aiello, Davis, Girach (bib59) 2006; 113 Patel (bib114) 2007; 370 Gillies, Wong (bib140) 2007; 356 (bib134) 2010; 117 Aiello (bib145) 2008; 359 Becerra, Amaral (bib69) 2002; 347 Cheung, Rogers, Donaghue, Jenkins, Tikellis, Wong (bib74) 2008; 31 Nguyen, Kawasaki, Wang (bib84) 2009; 32 Patel, MacMahon, Chalmers (bib104) 2008; 358 Doukas, Mahesh, Umeda (bib146) 2008; 216 (bib109) 2000; 342 Cheung, Wong (bib40) 2007; 52 Ambrosius, Danis, Goff (bib127) 2010; 128 Rema, Premkumar, Anitha, Deepa, Pradeepa, Mohan (bib16) 2005; 46 Yilmaz, Weaver, Gallagher (bib54) 2009; 116 Varma (bib26) 2008; 115 (bib37) 2000; 23 Nishikawa, Edelstein, Du (bib57) 2000; 404 Duckworth, Abraira, Moritz (bib107) 2009; 360 Saaddine, Honeycutt, Narayan, Zhang, Klein, Boyle (bib5) 2008; 126 (bib91) 1981; 88 McLeod (bib93) 2005; 89 Klein, Knudtson, Lee, Gangnon, Klein (bib28) 2009; 116 Mitchell, Wong (bib115) 2008; 372 (bib129) 2008; 115 (bib132) 1988; 95 (bib33) 1997; 46 Klein, Moss, Klein (bib34) 1990; 13 Nguyen, Alibrahim, Islam (bib73) 2009; 32 Schwartz, Flynn, Aiello (bib123) 2009; 45 Donaghue, Fairchild, Craig (bib35) 2003; 26 Xu, Chen, Forrester (bib72) 2009; 28 Conway, Miller, Klein, Orchard (bib42) 2009; 127 (bib131) 1985; 103 Xie, Xu, Wang, Jonas (bib15) 2008; 246 Genuth, Sun, Cleary (bib125) 2005; 54 Cheema, Al-Mubarak, Amin, Cheema (bib138) 2009; 35 Raymond, Varadhan, Reynold (bib12) 2009; 32 Nguyen, Kawasaki, Kreis (bib83) 2009; 34 Lonn, Yusuf, Hoogwerf (bib58) 2002; 25 Saaddine, Cadwell, Gregg (bib21) 2006; 144 Suzuma, Hata, Clermont (bib110) 2001; 50 Klein, Knudtson, Tsai, Klein (bib44) 2009; 127 Klein (bib25) 2008 Klein (bib39) 2006 Cheung, Rogers, Couper, Klein, Sharrett, Wong (bib45) 2007; 38 Sjolie, Klein, Porta (bib117) 2008; 372 Islam, Nguyen, Wang (bib81) 2009; 23 Fong, Aiello, Ferris, Klein (bib2) 2004; 27 Wirostko, Wong, Simo (bib64) 2008; 27 Klein, Klein, Knudtson, Wong, Tsai (bib82) 2006; 124 Kempen, O'Colmain, Leske (bib8) 2004; 122 Stolk, van Schooneveld, Cruickshank (bib30) 2008; 31 Chaturvedi, Porta, Klein (bib116) 2008; 372 Cheung, Donaghue, Liew (bib87) 2009; 32 Stefansson (bib130) 2009; 247 Mandecka, Dawczynski, Blum (bib88) 2007; 30 Cheung, Tikellis, Wang (bib75) 2007; 114 Einarsdottir, Stefansson (bib71) 2009; 373 Machalinska, Baumert, Kuprjanowicz, Wiszniewska, Karczewicz, Machalinski (bib144) 2009; 34 Katsura, Okano, Matsuno (bib66) 2005; 28 Younis, Broadbent, Vora, Harding (bib98) 2003; 361 Drexler, Fujimoto (bib97) 2008; 27 Genuth (bib108) 2006; 12 (bib100) 1998; 116 Davis, Sheetz, Aiello (bib124) 2009; 50 Mohamed, Wong (bib61) 2008; 13 Lyons, Jenkins, Zheng (bib119) 2004; 45 bib4 Aiello (bib51) 2005; 353 (bib135) 2010; 117 Bolton, Cattran, Williams (bib63) 2004; 24 Wilkinson, Ferris, Klein (bib94) 2003; 110 Shen, Child, Weber, Folkman, Aiello (bib126) 2008; 126 Abhary, Hewitt, Burdon, Craig (bib32) 2009; 58 Gardiner, Archer, Curtis, Stitt (bib76) 2007; 14 Rogers, Tikellis, Cheung (bib10) 2008; 31 Cheung, Wong (bib121) 2008; 371 Boyer, Heier, Brown, Francom, Ianchulev, Rubio (bib141) 2009; 116 Klein, Moss, Klein (bib38) 1990; 13 Mauer, Zinman, Gardiner (bib118) 2009; 361 Cheung, Wang, Rogers (bib47) 2008; 51 Gallego, Craig, Hing, Donaghue (bib111) 2008; 337 Klein, Klein, Moss (bib77) 2004; 122 Roy, Klein, O'Colmain, Klein, Moss, Kempen (bib9) 2004; 122 Ciulla, Amador, Zinman (bib50) 2003; 26 Liew, Mitchell, Wong (bib106) 2009; 338 Chaturvedi, Sjolie, Stephenson (bib113) 1998; 351 Wang, Wang, Wong (bib41) 2008; 53 Gardner, Antonetti (bib65) 2007; 13 Zhang, Wu, Jin (bib70) 2008; 49 Gao, Clermont, Rook (bib56) 2007; 13 Hoerger, Segel, Gregg, Saaddine (bib22) 2008; 31 (bib86) 1991; 338 Antonetti, Barber, Bronson (bib49) 2006; 55 Sloan, Belsky, Ruiz, Lee (bib18) 2008; 126 Wong, Klein, Islam (bib29) 2006; 141 Yang, Liu, Shi, Li (bib43) 2010; 33 Wang, Liang, Zhang (bib13) 2009; 116 Vasilaki, Thermos (bib62) 2009; 122 White, Sun, Cleary (bib101) 2008; 126 (bib60) 2007; 125 Watanabe, Suzuma, Matsui (bib55) 2005; 353 Raman, Rani, Reddi Rachepalle (bib17) 2009; 116 Klein (10.1016/S0140-6736(09)62124-3_bib38) 1990; 13 Ryan (10.1016/S0140-6736(09)62124-3_bib128) 2006; 26 Wong (10.1016/S0140-6736(09)62124-3_bib85) 2006; 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13 (10.1016/S0140-6736(09)62124-3_bib92) 1995; 113 Mitchell (10.1016/S0140-6736(09)62124-3_bib115) 2008; 372 Stolk (10.1016/S0140-6736(09)62124-3_bib30) 2008; 31 (10.1016/S0140-6736(09)62124-3_bib109) 2000; 342 Ciulla (10.1016/S0140-6736(09)62124-3_bib50) 2003; 26 Islam (10.1016/S0140-6736(09)62124-3_bib81) 2009; 23 Fong (10.1016/S0140-6736(09)62124-3_bib2) 2004; 27 Kim (10.1016/S0140-6736(09)62124-3_bib133) 2007; 114 Suzuma (10.1016/S0140-6736(09)62124-3_bib110) 2001; 50 Einarsdottir (10.1016/S0140-6736(09)62124-3_bib71) 2009; 373 Holman (10.1016/S0140-6736(09)62124-3_bib112) 2008; 359 Williams (10.1016/S0140-6736(09)62124-3_bib95) 2004; 111 Patel (10.1016/S0140-6736(09)62124-3_bib114) 2007; 370 Lyons (10.1016/S0140-6736(09)62124-3_bib119) 2004; 45 (10.1016/S0140-6736(09)62124-3_bib132) 1988; 95 Mohamed (10.1016/S0140-6736(09)62124-3_bib7) 2007; 298 Aiello (10.1016/S0140-6736(09)62124-3_bib145) 2008; 359 Gao (10.1016/S0140-6736(09)62124-3_bib56) 2007; 13 Lonn (10.1016/S0140-6736(09)62124-3_bib58) 2002; 25 (10.1016/S0140-6736(09)62124-3_bib33) 1997; 46 Chen (10.1016/S0140-6736(09)62124-3_bib67) 2009; 50 Nguyen (10.1016/S0140-6736(09)62124-3_bib83) 2009; 34 Xie (10.1016/S0140-6736(09)62124-3_bib15) 2008; 246 Gaede (10.1016/S0140-6736(09)62124-3_bib122) 2008; 358 Machalinska (10.1016/S0140-6736(09)62124-3_bib144) 2009; 34 (10.1016/S0140-6736(09)62124-3_bib86) 1991; 338 Genuth (10.1016/S0140-6736(09)62124-3_bib125) 2005; 54 Wong (10.1016/S0140-6736(09)62124-3_bib139) 2007; 370 Varma (10.1016/S0140-6736(09)62124-3_bib26) 2008; 115 Hoerger (10.1016/S0140-6736(09)62124-3_bib22) 2008; 31 Wong (10.1016/S0140-6736(09)62124-3_bib103) 2008; 371 Schwartz (10.1016/S0140-6736(09)62124-3_bib123) 2009; 45 (10.1016/S0140-6736(09)62124-3_bib37) 2000; 23 Yilmaz (10.1016/S0140-6736(09)62124-3_bib54) 2009; 116 (10.1016/S0140-6736(09)62124-3_bib134) 2010; 117 Klein (10.1016/S0140-6736(09)62124-3_bib77) 2004; 122 (10.1016/S0140-6736(09)62124-3_bib100) 1998; 116 Wong (10.1016/S0140-6736(09)62124-3_bib24) 2006; 90 (10.1016/S0140-6736(09)62124-3_bib135) 2010; 117 Cheung (10.1016/S0140-6736(09)62124-3_bib87) 2009; 32 Sjolie (10.1016/S0140-6736(09)62124-3_bib117) 2008; 372 Klein (10.1016/S0140-6736(09)62124-3_bib25) 2008 (10.1016/S0140-6736(09)62124-3_bib60) 2007; 125 Antonetti (10.1016/S0140-6736(09)62124-3_bib49) 2006; 55 Zhang (10.1016/S0140-6736(09)62124-3_bib70) 2008; 49 Roy (10.1016/S0140-6736(09)62124-3_bib9) 2004; 122 Duckworth (10.1016/S0140-6736(09)62124-3_bib107) 2009; 360 Cheung (10.1016/S0140-6736(09)62124-3_bib46) 2007; 30 Boyer (10.1016/S0140-6736(09)62124-3_bib141) 2009; 116 Maia (10.1016/S0140-6736(09)62124-3_bib143) 2009; 147 White (10.1016/S0140-6736(09)62124-3_bib102) 2010; 59 Mandecka (10.1016/S0140-6736(09)62124-3_bib88) 2007; 30 Wang (10.1016/S0140-6736(09)62124-3_bib41) 2008; 53 Klein (10.1016/S0140-6736(09)62124-3_bib27) 1995; 102 Sloan (10.1016/S0140-6736(09)62124-3_bib18) 2008; 126 Tikellis (10.1016/S0140-6736(09)62124-3_bib80) 2007; 50 Saaddine (10.1016/S0140-6736(09)62124-3_bib5) 2008; 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127 Wong (10.1016/S0140-6736(09)62124-3_bib14) 2008; 115 Hong (10.1016/S0140-6736(09)62124-3_bib136) 2009; 116 Klein (10.1016/S0140-6736(09)62124-3_bib28) 2009; 116 Cheung (10.1016/S0140-6736(09)62124-3_bib121) 2008; 371 Cheung (10.1016/S0140-6736(09)62124-3_bib45) 2007; 38 Raman (10.1016/S0140-6736(09)62124-3_bib17) 2009; 116 Cheung (10.1016/S0140-6736(09)62124-3_bib47) 2008; 51 Stefansson (10.1016/S0140-6736(09)62124-3_bib130) 2009; 247 Vasilaki (10.1016/S0140-6736(09)62124-3_bib62) 2009; 122 White (10.1016/S0140-6736(09)62124-3_bib101) 2008; 126 Cheema (10.1016/S0140-6736(09)62124-3_bib138) 2009; 35 Beck (10.1016/S0140-6736(09)62124-3_bib142) 2009; 127 (10.1016/S0140-6736(09)62124-3_bib99) 2000; 23 Ambrosius (10.1016/S0140-6736(09)62124-3_bib127) 2010; 128 Grover (10.1016/S0140-6736(09)62124-3_bib53) 2008 Chan (10.1016/S0140-6736(09)62124-3_bib23) 2009; 301 Curtis (10.1016/S0140-6736(09)62124-3_bib48) 2009; 23 Shen (10.1016/S0140-6736(09)62124-3_bib126) 2008; 126 Nguyen (10.1016/S0140-6736(09)62124-3_bib84) 2009; 32 Younis (10.1016/S0140-6736(09)62124-3_bib98) 2003; 361 Klein (10.1016/S0140-6736(09)62124-3_bib82) 2006; 124 Davis (10.1016/S0140-6736(09)62124-3_bib124) 2009; 50 Wirostko (10.1016/S0140-6736(09)62124-3_bib64) 2008; 27 Katsura (10.1016/S0140-6736(09)62124-3_bib66) 2005; 28 Yang (10.1016/S0140-6736(09)62124-3_bib43) 2010; 33 Watanabe (10.1016/S0140-6736(09)62124-3_bib55) 2005; 353 Nguyen (10.1016/S0140-6736(09)62124-3_bib78) 2008; 31 Takamura (10.1016/S0140-6736(09)62124-3_bib137) 2009; 116 Xu (10.1016/S0140-6736(09)62124-3_bib72) 2009; 28
References_xml	– volume: 30 start-page: 2902 year: 2007 end-page: 2908 ident: bib11 article-title: Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration publication-title: Diabetes Care – volume: 23 start-page: 1719 year: 2009 end-page: 1724 ident: bib81 article-title: Quantitative retinal vascular calibre changes in diabetes and retinopathy: the Singapore Malay Eye Study publication-title: Eye – volume: 115 start-page: 1447 year: 2008 end-page: 1449 ident: bib129 article-title: A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema publication-title: Ophthalmology – volume: 31 start-page: 761 year: 2008 end-page: 763 ident: bib10 article-title: Retinal arteriolar caliber predicts incident retinopathy: the Australia Diabetes, Obesity and Lifestyle (AusDiab) Study publication-title: Diabetes Care – volume: 33 start-page: 1018 year: 2010 end-page: 1020 ident: bib43 article-title: An association between subclinical hypothyroidism and sight-threatening diabetic retinopathy In type 2 diabetic patients publication-title: Diabetes Care – volume: 90 start-page: 506 year: 2006 end-page: 511 ident: bib24 article-title: The epidemiology of age related eye diseases in Asia publication-title: Br J Ophthalmol – volume: 49 start-page: 35 year: 2009 end-page: 52 ident: bib31 article-title: The role of genetics in susceptibility to diabetic retinopathy publication-title: Int Ophthalmol Clin – volume: 13 start-page: 1034 year: 1990 end-page: 1038 ident: bib34 article-title: Is menarche associated with diabetic retinopathy? publication-title: Diabetes Care – volume: 122 start-page: 76 year: 2004 end-page: 83 ident: bib77 article-title: The relation of retinal vessel caliber to the incidence and progression of diabetic retinopathy: XIX: the Wisconsin Epidemiologic Study of Diabetic Retinopathy publication-title: Arch Ophthalmol – volume: 404 start-page: 787 year: 2000 end-page: 790 ident: bib57 article-title: Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage publication-title: Nature – volume: 247 start-page: 147 year: 2009 end-page: 163 ident: bib130 article-title: Physiology of vitreous surgery publication-title: Graefes Arch Clin Exp Ophthalmol – volume: 23 start-page: 73 year: 2000 end-page: 76 ident: bib99 article-title: Diabetic retinopathy publication-title: Diabetes Care – volume: 31 start-page: 1842 year: 2008 end-page: 1846 ident: bib74 article-title: Retinal arteriolar dilation predicts retinopathy in adolescents with type 1 diabetes publication-title: Diabetes Care – volume: 147 start-page: 291 year: 2009 end-page: 297 ident: bib143 article-title: Combined laser and intravitreal triamcinolone for proliferative diabetic retinopathy and macular edema: one-year results of a randomized clinical trial publication-title: Am J Ophthalmol – volume: 126 start-page: 1548 year: 2008 end-page: 1553 ident: bib18 article-title: Changes in incidence of diabetes mellitus-related eye disease among US elderly persons, 1994–2005 publication-title: Arch Ophthalmol – volume: 115 start-page: 1869 year: 2008 end-page: 1875 ident: bib14 article-title: Prevalence and risk factors for diabetic retinopathy: the Singapore Malay Eye Study publication-title: Ophthalmology – volume: 371 start-page: 721 year: 2008 end-page: 722 ident: bib121 article-title: Fenofibrate and diabetic retinopathy publication-title: Lancet – volume: 127 start-page: 1494 year: 2009 end-page: 1499 ident: bib42 article-title: Prediction of proliferative diabetic retinopathy with hemoglobin level publication-title: Arch Ophthalmol – volume: 14 start-page: 25 year: 2007 end-page: 38 ident: bib76 article-title: Arteriolar involvement in the microvascular lesions of diabetic retinopathy: implications for pathogenesis publication-title: Microcirculation – volume: 35 start-page: 18 year: 2009 end-page: 25 ident: bib138 article-title: Role of combined cataract surgery and intravitreal bevacizumab injection in preventing progression of diabetic retinopathy: prospective randomized study publication-title: J Cataract Refract Surg – volume: 18 start-page: 160 year: 2004 end-page: 164 ident: bib36 article-title: The significance of the prepubertal diabetes duration for the development of retinopathy and nephropathy in patients with type 1 diabetes publication-title: J Diabetes Complications – volume: 47 start-page: 2341 year: 2006 end-page: 2350 ident: bib85 article-title: Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA) publication-title: Invest Ophthalmol Vis Sci – volume: 331 start-page: 1480 year: 1994 end-page: 1487 ident: bib52 article-title: Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders publication-title: N Engl J Med – volume: 31 start-page: 544 year: 2008 end-page: 549 ident: bib78 article-title: Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Diabetes Care – volume: XI start-page: 1 year: 1993 end-page: 14 ident: bib89 article-title: Diabetic retinopathy: classification, progression and management publication-title: Focal Points (American Academy of Ophthalmology) – volume: 50 start-page: 1329 year: 2009 end-page: 1335 ident: bib67 article-title: Suppression of retinal neovascularization by erythropoietin siRNA in a mouse model of proliferative retinopathy publication-title: Invest Ophthalmol Vis Sci – volume: 31 start-page: 1189 year: 2008 end-page: 1194 ident: bib68 article-title: Expression of erythropoietin and its receptor in the human retina: a comparative study of diabetic and nondiabetic subjects publication-title: Diabetes Care – volume: 360 start-page: 129 year: 2009 end-page: 139 ident: bib107 article-title: Glucose control and vascular complications in veterans with type 2 diabetes publication-title: N Engl J Med – volume: 116 start-page: 461 year: 2009 end-page: 467 ident: bib13 article-title: Prevalence of diabetic retinopathy in rural China: the Handan Eye Study publication-title: Ophthalmology – volume: 34 start-page: 748 year: 2009 end-page: 760 ident: bib144 article-title: Potential application of adult stem cells in retinal repair–challenge for regenerative medicine publication-title: Curr Eye Res – volume: 372 start-page: 1394 year: 2008 end-page: 1402 ident: bib116 article-title: Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials publication-title: Lancet – volume: 116 start-page: 1731 year: 2009 end-page: 1739 ident: bib141 article-title: A Phase IIIb study to evaluate the safety of ranibizumab in subjects with neovascular age-related macular degeneration publication-title: Ophthalmology – volume: 113 start-page: 1144 year: 1995 end-page: 1155 ident: bib92 article-title: Focal photocoagulation treatment of diabetic macular edema. Relationship of treatment effect to fluorescein angiographic and other retinal characteristics at baseline: ETDRS report no. 19 publication-title: Arch Ophthalmol – volume: 31 start-page: 1905 year: 2008 end-page: 1912 ident: bib3 article-title: Ocular associations of diabetes other than diabetic retinopathy publication-title: Diabetes Care – volume: 290 start-page: 2057 year: 2003 end-page: 2060 ident: bib1 article-title: Important causes of visual impairment in the world today publication-title: JAMA – volume: 114 start-page: 2098 year: 2007 end-page: 2099 ident: bib75 article-title: Diabetic retinopathy publication-title: Ophthalmology – volume: 30 start-page: 3048 year: 2007 end-page: 3052 ident: bib88 article-title: Influence of flickering light on the retinal vessels in diabetic patients publication-title: Diabetes Care – volume: 31 start-page: 708 year: 2008 end-page: 713 ident: bib30 article-title: Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes: baseline results from the ADVANCE Retinal Measurements (AdRem) study publication-title: Diabetes Care – volume: 26 start-page: 1224 year: 2003 end-page: 1229 ident: bib35 article-title: Do all prepubertal years of diabetes duration contribute equally to diabetes complications? publication-title: Diabetes Care – volume: 26 start-page: 2653 year: 2003 end-page: 2664 ident: bib50 article-title: Diabetic retinopathy and diabetic macular edema: pathophysiology, screening, and novel therapies publication-title: Diabetes Care – volume: 370 start-page: 204 year: 2007 end-page: 206 ident: bib139 article-title: Clinical update: new treatments for age-related macular degeneration publication-title: Lancet – volume: 115 start-page: 1857 year: 2008 end-page: 1858 ident: bib26 article-title: From a population to patients: the Wisconsin epidemiologic study of diabetic retinopathy publication-title: Ophthalmology – volume: 111 start-page: 1055 year: 2004 end-page: 1062 ident: bib95 article-title: Single-field fundus photography for diabetic retinopathy screening: a report by the American Academy of Ophthalmology publication-title: Ophthalmology – volume: 298 start-page: 902 year: 2007 end-page: 916 ident: bib7 article-title: Management of diabetic retinopathy: a systematic review publication-title: JAMA – year: 2008 ident: bib53 article-title: Intravitreal steroids for macular edema in diabetes publication-title: Cochrane Database Syst Rev – volume: 116 start-page: 902 year: 2009 end-page: 911 ident: bib54 article-title: Intravitreal triamcinolone acetonide injection for treatment of refractory diabetic macular edema: a systematic review publication-title: Ophthalmology – volume: 13 start-page: 131 year: 2007 end-page: 132 ident: bib65 article-title: A prize catch for diabetic retinopathy publication-title: Nat Med – volume: 31 start-page: 81 year: 2008 end-page: 86 ident: bib22 article-title: Is glycemic control improving in U.S. adults? publication-title: Diabetes Care – volume: 301 start-page: 2129 year: 2009 end-page: 2140 ident: bib23 article-title: Diabetes in Asia: epidemiology, risk factors, and pathophysiology publication-title: JAMA – volume: 24 start-page: 32 year: 2004 end-page: 40 ident: bib63 article-title: Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy publication-title: Am J Nephrol – volume: 141 start-page: 446 year: 2006 end-page: 455 ident: bib29 article-title: Diabetic retinopathy in a multi-ethnic cohort in the United States publication-title: Am J Ophthalmol – volume: 370 start-page: 829 year: 2007 end-page: 840 ident: bib114 article-title: Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial publication-title: Lancet – volume: 127 start-page: 1175 year: 2009 end-page: 1182 ident: bib44 article-title: The relation of markers of inflammation and endothelial dysfunction to the prevalence and progression of diabetic retinopathy: Wisconsin epidemiologic study of diabetic retinopathy publication-title: Arch Ophthalmol – volume: 125 start-page: 318 year: 2007 end-page: 324 ident: bib60 article-title: Effect of ruboxistaurin in patients with diabetic macular edema: thirty-month results of the randomized PKC-DMES clinical trial publication-title: Arch Ophthalmol – volume: 49 start-page: 732 year: 2008 end-page: 742 ident: bib70 article-title: Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes publication-title: Invest Ophthalmol Vis Sci – volume: 246 start-page: 1519 year: 2008 end-page: 1526 ident: bib15 article-title: Prevalence and associated factors of diabetic retinopathy. The Beijing Eye Study 2006 publication-title: Graefes Arch Clin Exp Ophthalmol – volume: 27 start-page: 45 year: 2008 end-page: 88 ident: bib97 article-title: State-of-the-art retinal optical coherence tomography publication-title: Prog Retin Eye Res – volume: 359 start-page: 967 year: 2008 end-page: 969 ident: bib145 article-title: Targeting intraocular neovascularization and edema–one drop at a time publication-title: N Engl J Med – volume: 116 start-page: 1151 year: 2009 end-page: 1157 ident: bib137 article-title: Analysis of the effect of intravitreal bevacizumab injection on diabetic macular edema after cataract surgery publication-title: Ophthalmology – volume: 361 start-page: 195 year: 2003 end-page: 200 ident: bib98 article-title: Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study publication-title: Lancet – volume: 54 start-page: 3103 year: 2005 end-page: 3111 ident: bib125 article-title: Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes publication-title: Diabetes – volume: 128 start-page: 312 year: 2010 end-page: 318 ident: bib127 article-title: Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy publication-title: Arch Ophthalmol – volume: 103 start-page: 1644 year: 1985 end-page: 1652 ident: bib131 article-title: Early vitrectomy for severe vitreous hemorrhage in diabetic retinopathy. Two-year results of a randomized trial. Diabetic Retinopathy Vitrectomy Study report 2 publication-title: Arch Ophthalmol – volume: 126 start-page: 1740 year: 2008 end-page: 1747 ident: bib5 article-title: Projection of diabetic retinopathy and other major eye diseases among people with diabetes mellitus: United States, 2005–2050 publication-title: Arch Ophthalmol – volume: 51 start-page: 1573 year: 2008 end-page: 1578 ident: bib47 article-title: Diabetic retinopathy and risk of heart failure publication-title: J Am Coll Cardiol – volume: 124 start-page: 87 year: 2006 end-page: 94 ident: bib82 article-title: Are inflammatory factors related to retinal vessel caliber? The Beaver Dam Eye Study publication-title: Arch Ophthalmol – volume: 30 start-page: 1742 year: 2007 end-page: 1746 ident: bib46 article-title: Diabetic retinopathy and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study publication-title: Diabetes Care – volume: 359 start-page: 1565 year: 2008 end-page: 1576 ident: bib112 article-title: Long-term follow-up after tight control of blood pressure in type 2 diabetes publication-title: N Engl J Med – volume: 342 start-page: 381 year: 2000 end-page: 389 ident: bib109 article-title: Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy publication-title: N Engl J Med – volume: 370 start-page: 1687 year: 2007 end-page: 1697 ident: bib120 article-title: Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial publication-title: Lancet – volume: 28 start-page: 348 year: 2009 end-page: 368 ident: bib72 article-title: Para-inflammation in the aging retina publication-title: Prog Retin Eye Res – volume: 110 start-page: 1677 year: 2003 end-page: 1682 ident: bib94 article-title: Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales publication-title: Ophthalmology – volume: 113 start-page: 2221 year: 2006 end-page: 2230 ident: bib59 article-title: Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy publication-title: Ophthalmology – volume: 351 start-page: 28 year: 1998 end-page: 31 ident: bib113 article-title: Effect of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes. The EUCLID Study Group publication-title: Lancet – volume: 38 start-page: 398 year: 2007 end-page: 401 ident: bib45 article-title: Is diabetic retinopathy an independent risk factor for ischemic stroke? publication-title: Stroke – volume: 32 start-page: 410 year: 2009 end-page: 415 ident: bib12 article-title: Higher prevalence of retinopathy in diabetic patients of South Asian ethnicity compared with white Europeans in the community: a cross-sectional study publication-title: Diabetes Care – volume: 353 start-page: 839 year: 2005 end-page: 841 ident: bib51 article-title: Angiogenic pathways in diabetic retinopathy publication-title: N Engl J Med – volume: 25 start-page: 1919 year: 2002 end-page: 1927 ident: bib58 article-title: Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: results of the HOPE study and MICRO-HOPE substudy publication-title: Diabetes Care – volume: 353 start-page: 782 year: 2005 end-page: 792 ident: bib55 article-title: Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy publication-title: N Engl J Med – volume: 89 start-page: 229 year: 2005 end-page: 237 ident: bib93 article-title: Why cotton wool spots should not be regarded as retinal nerve fibre layer infarcts publication-title: Br J Ophthalmol – volume: 361 start-page: 40 year: 2009 end-page: 51 ident: bib118 article-title: Renal and retinal effects of enalapril and losartan in type 1 diabetes publication-title: N Engl J Med – volume: 115 start-page: 1859 year: 2008 end-page: 1868 ident: bib20 article-title: The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XXII the twenty-five-year progression of retinopathy in persons with type 1 diabetes publication-title: Ophthalmology – volume: 58 start-page: 2137 year: 2009 end-page: 2147 ident: bib32 article-title: A systematic meta-analysis of genetic association studies for diabetic retinopathy publication-title: Diabetes – volume: 55 start-page: 2401 year: 2006 end-page: 2411 ident: bib49 article-title: Diabetic retinopathy: seeing beyond glucose-induced microvascular disease publication-title: Diabetes – volume: 358 start-page: 2545 year: 2008 end-page: 2559 ident: bib105 article-title: Effects of intensive glucose lowering in type 2 diabetes publication-title: N Engl J Med – volume: 50 start-page: 1 year: 2009 end-page: 4 ident: bib124 article-title: Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema publication-title: Invest Ophthalmol Vis Sci – volume: 126 start-page: 793 year: 2008 end-page: 799 ident: bib126 article-title: Rosiglitazone and delayed onset of proliferative diabetic retinopathy publication-title: Arch Ophthalmol – volume: 144 start-page: 465 year: 2006 end-page: 474 ident: bib21 article-title: Improvements in diabetes processes of care and intermediate outcomes: United States, 1988–2002 publication-title: Ann Intern Med – volume: 13 start-page: 34 year: 1990 end-page: 40 ident: bib38 article-title: Effect of pregnancy on progression of diabetic retinopathy publication-title: Diabetes Care – volume: 116 start-page: 311 year: 2009 end-page: 318 ident: bib17 article-title: Prevalence of diabetic retinopathy in India: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study report 2 publication-title: Ophthalmology – volume: 116 start-page: 1510 year: 2009 end-page: 1514 ident: bib136 article-title: Development and progression of diabetic retinopathy 12 months after phacoemulsification cataract surgery publication-title: Ophthalmology – volume: 338 start-page: b441 year: 2009 ident: bib106 article-title: Systemic management of diabetic retinopathy publication-title: BMJ – volume: 127 start-page: 245 year: 2009 end-page: 251 ident: bib142 article-title: Three-year follow-up of a randomized trial comparing focal/grid photocoagulation and intravitreal triamcinolone for diabetic macular edema publication-title: Arch Ophthalmol – year: 2008 ident: bib25 article-title: Epidemiology of Diabetic Retinopathy publication-title: Diabetic Retinopathy – volume: 117 start-page: 1067 year: 2010 end-page: 1077 ident: bib135 article-title: Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema publication-title: Ophthalmology – volume: 32 start-page: 1704 year: 2009 end-page: 1709 ident: bib73 article-title: Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: the multi-ethnic study of atherosclerosis publication-title: Diabetes Care – volume: 53 start-page: 512 year: 2008 end-page: 525 ident: bib41 article-title: Alcohol and eye diseases publication-title: Surv Ophthalmol – volume: 116 start-page: 874 year: 1998 end-page: 886 ident: bib100 article-title: Early worsening of diabetic retinopathy in the Diabetes Control and Complications Trial publication-title: Arch Ophthalmol – volume: 27 start-page: 2540 year: 2004 end-page: 2553 ident: bib2 article-title: Diabetic retinopathy publication-title: Diabetes Care – volume: 122 start-page: 324 year: 2009 end-page: 333 ident: bib62 article-title: Somatostatin analogues as therapeutics in retinal disease publication-title: Pharmacol Ther – volume: 50 start-page: 444 year: 2001 end-page: 454 ident: bib110 article-title: Cyclic stretch and hypertension induce retinal expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2: potential mechanisms for exacerbation of diabetic retinopathy by hypertension publication-title: Diabetes – volume: 122 start-page: 546 year: 2004 end-page: 551 ident: bib9 article-title: The prevalence of diabetic retinopathy among adult type 1 diabetic persons in the United States publication-title: Arch Ophthalmol – volume: 27 start-page: 608 year: 2008 end-page: 621 ident: bib64 article-title: Vascular endothelial growth factor and diabetic complications publication-title: Prog Retin Eye Res – volume: 126 start-page: 1707 year: 2008 end-page: 1715 ident: bib101 article-title: Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial publication-title: Arch Ophthalmol – volume: 337 start-page: a918 year: 2008 ident: bib111 article-title: Role of blood pressure in development of early retinopathy in adolescents with type 1 diabetes: prospective cohort study publication-title: BMJ – volume: 372 start-page: 1361 year: 2008 end-page: 1363 ident: bib115 article-title: DIRECT new treatments for diabetic retinopathy publication-title: Lancet – volume: 12 start-page: 34 year: 2006 end-page: 41 ident: bib108 article-title: Insights from the diabetes control and complications trial/epidemiology of diabetes interventions and complications study on the use of intensive glycemic treatment to reduce the risk of complications of type 1 diabetes publication-title: Endocr Pract – volume: 50 start-page: 2263 year: 2007 end-page: 2271 ident: bib80 article-title: The relationship of retinal vascular calibre to diabetes and retinopathy: the Australian Diabetes, Obesity and Lifestyle (AusDiab) study publication-title: Diabetologia – volume: 32 start-page: 2075 year: 2009 end-page: 2080 ident: bib84 article-title: Flicker light-induced retinal vasodilation in diabetes and diabetic retinopathy publication-title: Diabetes Care – volume: 356 start-page: 748 year: 2007 end-page: 749 ident: bib140 article-title: Ranibizumab for neovascular age-related macular degeneration publication-title: N Engl J Med – volume: 347 start-page: 1968 year: 2002 end-page: 1970 ident: bib69 article-title: Erythropoietin—an endogenous retinal survival factor publication-title: N Engl J Med – volume: 118 start-page: 2337 year: 2008 end-page: 2346 ident: bib147 article-title: Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits publication-title: J Clin Invest – volume: 358 start-page: 2560 year: 2008 end-page: 2572 ident: bib104 article-title: Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes publication-title: N Engl J Med – volume: 116 start-page: 1937 year: 2009 end-page: 1942 ident: bib19 article-title: Changes in visual impairment prevalence by period of diagnosis of diabetes the Wisconsin Epidemiologic Study of Diabetic Retinopathy publication-title: Ophthalmology – year: 2006 ident: bib39 article-title: Diabetic retinopathy and nephropathy publication-title: The diabetic kidney – volume: 13 start-page: 181 year: 2007 end-page: 188 ident: bib56 article-title: Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation publication-title: Nat Med – volume: 23 start-page: 1496 year: 2009 end-page: 1508 ident: bib48 article-title: Microvascular lesions of diabetic retinopathy: clues towards understanding pathogenesis? publication-title: Eye – volume: 372 start-page: 1385 year: 2008 end-page: 1393 ident: bib117 article-title: Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial publication-title: Lancet – volume: 34 start-page: 1082 year: 2009 end-page: 1088 ident: bib83 article-title: Correlation of flicker-light induced retinal vasodilation and retinal vascular caliber measurements in diabetes publication-title: Invest Ophthalmol Vis Sci – volume: 373 start-page: 1316 year: 2009 end-page: 1318 ident: bib71 article-title: Prevention of diabetic retinopathy publication-title: Lancet – volume: 117 start-page: 1087 year: 2010 end-page: 1093 ident: bib134 article-title: Diabetic Retinopathy Clinical Research Network Writing Committee on behalf of the DRCR.net. Vitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction publication-title: Ophthalmology – volume: 52 start-page: 180 year: 2007 end-page: 195 ident: bib40 article-title: Obesity and Eye Diseases publication-title: Survey of Ophthalmology – volume: 113 start-page: 1488 year: 2006 end-page: 1498 ident: bib79 article-title: Retinal vascular caliber in persons with type 2 diabetes: the Wisconsin Epidemiological Study of Diabetic Retinopathy: 20 publication-title: Ophthalmology – volume: 45 start-page: 269 year: 2009 end-page: 274 ident: bib123 article-title: Ruboxistaurin mesilate hydrate for diabetic retinopathy publication-title: Drugs Today (Barc) – volume: 46 start-page: 1829 year: 1997 end-page: 1839 ident: bib33 article-title: Clustering of long-term complications in families with diabetes in the diabetes control and complications trial publication-title: Diabetes – volume: 13 start-page: 675 year: 2008 end-page: 694 ident: bib61 article-title: Emerging drugs for diabetic retinopathy publication-title: Expert Opin Emerg Drugs – volume: 338 start-page: 1425 year: 1991 end-page: 1426 ident: bib86 article-title: Fractals and medicine publication-title: Lancet – volume: 116 start-page: 497 year: 2009 end-page: 503 ident: bib28 article-title: The Wisconsin Epidemiologic Study of diabetic retinopathy XXIII: the twenty-five-year incidence of macular edema in persons with type 1 diabetes publication-title: Ophthalmology – volume: 23 start-page: 1084 year: 2000 end-page: 1091 ident: bib37 article-title: Effect of pregnancy on microvascular complications in the diabetes control and complications trial publication-title: Diabetes Care – volume: 46 start-page: 2328 year: 2005 end-page: 2333 ident: bib16 article-title: Prevalence of diabetic retinopathy in urban India: the Chennai Urban Rural Epidemiology Study (CURES) eye study, I publication-title: Invest Ophthalmol Vis Sci – volume: 59 start-page: 1244 year: 2010 end-page: 1253 ident: bib102 article-title: Effect of prior intensive therapy in type 1 diabetes mellitus on 10-year progression of retinopathy in the DCCT/EDIC: comparison of adults and adolescents publication-title: Diabetes – volume: 95 start-page: 1307 year: 1988 end-page: 1320 ident: bib132 article-title: Early vitrectomy for severe proliferative diabetic retinopathy in eyes with useful vision. Results of a randomized trial–Diabetic Retinopathy Vitrectomy Study Report 3 publication-title: Ophthalmology – volume: 26 start-page: 562 year: 2006 end-page: 570 ident: bib128 article-title: Diabetic macular edema associated with glitazone use publication-title: Retina – volume: 6 start-page: 428 year: 2008 end-page: 434 ident: bib96 article-title: Accuracy of primary care clinicians in screening for diabetic retinopathy using single-image retinal photography publication-title: Ann Fam Med – volume: 371 start-page: 736 year: 2008 end-page: 743 ident: bib103 article-title: Relation between fasting glucose and retinopathy for diagnosis of diabetes: three population-based cross-sectional studies publication-title: Lancet – volume: 216 start-page: 29 year: 2008 end-page: 37 ident: bib146 article-title: Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema publication-title: J Cell Physiol – ident: bib4 article-title: Diabetes atlas 2007 – volume: 45 start-page: 910 year: 2004 end-page: 918 ident: bib119 article-title: Diabetic retinopathy and serum lipoprotein subclasses in the DCCT/EDIC cohort publication-title: Invest Ophthalmol Vis Sci – volume: 114 start-page: 881 year: 2007 end-page: 889 ident: bib133 article-title: Analysis of macular edema after cataract surgery in patients with diabetes using optical coherence tomography publication-title: Ophthalmology – volume: 32 start-page: 106 year: 2009 end-page: 110 ident: bib87 article-title: Quantitative assessment of early diabetic retinopathy using fractal analysis publication-title: Diabetes Care – volume: 122 start-page: 552 year: 2004 end-page: 563 ident: bib8 article-title: The prevalence of diabetic retinopathy among adults in the United States publication-title: Arch Ophthalmol – volume: 102 start-page: 7 year: 1995 end-page: 16 ident: bib27 article-title: The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XV. The long-term incidence of macular edema publication-title: Ophthalmology – volume: 358 start-page: 580 year: 2008 end-page: 591 ident: bib122 article-title: Effect of a multifactorial intervention on mortality in type 2 diabetes publication-title: N Engl J Med – volume: 88 start-page: 583 year: 1981 end-page: 600 ident: bib91 article-title: Photocoagulation treatment of proliferative diabetic retinopathy. Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS Report Number 8 publication-title: Ophthalmology – volume: 28 start-page: 2252 year: 2005 end-page: 2254 ident: bib66 article-title: Erythropoietin is highly elevated in vitreous fluid of patients with proliferative diabetic retinopathy publication-title: Diabetes Care – volume: 98 start-page: 766 year: 1991 end-page: 785 ident: bib90 article-title: Early photocoagulation for diabetic retinopathy. ETDRS report number 9 publication-title: Ophthalmology – volume: 27 start-page: 161 year: 2008 end-page: 176 ident: bib6 article-title: Diabetic retinopathy and systemic vascular complications publication-title: Prog Retin Eye Res – volume: 30 start-page: 1742 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib46 article-title: Diabetic retinopathy and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study publication-title: Diabetes Care doi: 10.2337/dc07-0264 – volume: 122 start-page: 546 year: 2004 ident: 10.1016/S0140-6736(09)62124-3_bib9 article-title: The prevalence of diabetic retinopathy among adult type 1 diabetic persons in the United States publication-title: Arch Ophthalmol doi: 10.1001/archopht.122.4.546 – volume: 38 start-page: 398 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib45 article-title: Is diabetic retinopathy an independent risk factor for ischemic stroke? publication-title: Stroke doi: 10.1161/01.STR.0000254547.91276.50 – volume: XI start-page: 1 year: 1993 ident: 10.1016/S0140-6736(09)62124-3_bib89 article-title: Diabetic retinopathy: classification, progression and management publication-title: Focal Points (American Academy of Ophthalmology) – volume: 298 start-page: 902 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib7 article-title: Management of diabetic retinopathy: a systematic review publication-title: JAMA doi: 10.1001/jama.298.8.902 – volume: 122 start-page: 324 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib62 article-title: Somatostatin analogues as therapeutics in retinal disease publication-title: Pharmacol Ther doi: 10.1016/j.pharmthera.2009.03.010 – volume: 353 start-page: 839 year: 2005 ident: 10.1016/S0140-6736(09)62124-3_bib51 article-title: Angiogenic pathways in diabetic retinopathy publication-title: N Engl J Med doi: 10.1056/NEJMe058142 – volume: 116 start-page: 1510 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib136 article-title: Development and progression of diabetic retinopathy 12 months after phacoemulsification cataract surgery publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.03.003 – volume: 116 start-page: 1731 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib141 article-title: A Phase IIIb study to evaluate the safety of ranibizumab in subjects with neovascular age-related macular degeneration publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.05.024 – volume: 34 start-page: 1082 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib83 article-title: Correlation of flicker-light induced retinal vasodilation and retinal vascular caliber measurements in diabetes publication-title: Invest Ophthalmol Vis Sci – volume: 111 start-page: 1055 year: 2004 ident: 10.1016/S0140-6736(09)62124-3_bib95 article-title: Single-field fundus photography for diabetic retinopathy screening: a report by the American Academy of Ophthalmology publication-title: Ophthalmology doi: 10.1016/j.ophtha.2004.02.004 – volume: 127 start-page: 245 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib142 article-title: Three-year follow-up of a randomized trial comparing focal/grid photocoagulation and intravitreal triamcinolone for diabetic macular edema publication-title: Arch Ophthalmol doi: 10.1001/archophthalmol.2008.610 – volume: 372 start-page: 1385 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib117 article-title: Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial publication-title: Lancet doi: 10.1016/S0140-6736(08)61411-7 – volume: 404 start-page: 787 year: 2000 ident: 10.1016/S0140-6736(09)62124-3_bib57 article-title: Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage publication-title: Nature doi: 10.1038/35008121 – volume: 373 start-page: 1316 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib71 article-title: Prevention of diabetic retinopathy publication-title: Lancet doi: 10.1016/S0140-6736(09)60750-9 – volume: 358 start-page: 2560 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib104 article-title: Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes publication-title: N Engl J Med doi: 10.1056/NEJMoa0802987 – volume: 127 start-page: 1175 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib44 article-title: The relation of markers of inflammation and endothelial dysfunction to the prevalence and progression of diabetic retinopathy: Wisconsin epidemiologic study of diabetic retinopathy publication-title: Arch Ophthalmol doi: 10.1001/archophthalmol.2009.172 – volume: 372 start-page: 1394 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib116 article-title: Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials publication-title: Lancet doi: 10.1016/S0140-6736(08)61412-9 – volume: 46 start-page: 2328 year: 2005 ident: 10.1016/S0140-6736(09)62124-3_bib16 article-title: Prevalence of diabetic retinopathy in urban India: the Chennai Urban Rural Epidemiology Study (CURES) eye study, I publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.05-0019 – volume: 338 start-page: b441 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib106 article-title: Systemic management of diabetic retinopathy publication-title: BMJ doi: 10.1136/bmj.b441 – volume: 126 start-page: 793 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib126 article-title: Rosiglitazone and delayed onset of proliferative diabetic retinopathy publication-title: Arch Ophthalmol doi: 10.1001/archopht.126.6.793 – volume: 115 start-page: 1859 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib20 article-title: The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XXII the twenty-five-year progression of retinopathy in persons with type 1 diabetes publication-title: Ophthalmology doi: 10.1016/j.ophtha.2008.08.023 – volume: 33 start-page: 1018 year: 2010 ident: 10.1016/S0140-6736(09)62124-3_bib43 article-title: An association between subclinical hypothyroidism and sight-threatening diabetic retinopathy In type 2 diabetic patients publication-title: Diabetes Care doi: 10.2337/dc09-1784 – volume: 35 start-page: 18 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib138 article-title: Role of combined cataract surgery and intravitreal bevacizumab injection in preventing progression of diabetic retinopathy: prospective randomized study publication-title: J Cataract Refract Surg doi: 10.1016/j.jcrs.2008.09.019 – volume: 23 start-page: 1719 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib81 article-title: Quantitative retinal vascular calibre changes in diabetes and retinopathy: the Singapore Malay Eye Study publication-title: Eye doi: 10.1038/eye.2008.362 – volume: 372 start-page: 1361 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib115 article-title: DIRECT new treatments for diabetic retinopathy publication-title: Lancet doi: 10.1016/S0140-6736(08)61413-0 – volume: 216 start-page: 29 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib146 article-title: Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema publication-title: J Cell Physiol doi: 10.1002/jcp.21426 – year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib53 article-title: Intravitreal steroids for macular edema in diabetes publication-title: Cochrane Database Syst Rev doi: 10.1002/14651858.CD005656.pub2 – volume: 26 start-page: 2653 year: 2003 ident: 10.1016/S0140-6736(09)62124-3_bib50 article-title: Diabetic retinopathy and diabetic macular edema: pathophysiology, screening, and novel therapies publication-title: Diabetes Care doi: 10.2337/diacare.26.9.2653 – year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib25 article-title: Epidemiology of Diabetic Retinopathy – volume: 127 start-page: 1494 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib42 article-title: Prediction of proliferative diabetic retinopathy with hemoglobin level publication-title: Arch Ophthalmol doi: 10.1001/archophthalmol.2009.274 – volume: 47 start-page: 2341 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib85 article-title: Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA) publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.05-1539 – volume: 337 start-page: a918 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib111 article-title: Role of blood pressure in development of early retinopathy in adolescents with type 1 diabetes: prospective cohort study publication-title: BMJ doi: 10.1136/bmj.a918 – volume: 32 start-page: 410 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib12 article-title: Higher prevalence of retinopathy in diabetic patients of South Asian ethnicity compared with white Europeans in the community: a cross-sectional study publication-title: Diabetes Care doi: 10.2337/dc08-1422 – volume: 55 start-page: 2401 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib49 article-title: Diabetic retinopathy: seeing beyond glucose-induced microvascular disease publication-title: Diabetes doi: 10.2337/db05-1635 – volume: 358 start-page: 2545 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib105 article-title: Effects of intensive glucose lowering in type 2 diabetes publication-title: N Engl J Med doi: 10.1056/NEJMoa0802743 – volume: 358 start-page: 580 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib122 article-title: Effect of a multifactorial intervention on mortality in type 2 diabetes publication-title: N Engl J Med doi: 10.1056/NEJMoa0706245 – volume: 25 start-page: 1919 year: 2002 ident: 10.1016/S0140-6736(09)62124-3_bib58 article-title: Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: results of the HOPE study and MICRO-HOPE substudy publication-title: Diabetes Care doi: 10.2337/diacare.25.11.1919 – volume: 31 start-page: 1189 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib68 article-title: Expression of erythropoietin and its receptor in the human retina: a comparative study of diabetic and nondiabetic subjects publication-title: Diabetes Care doi: 10.2337/dc07-2075 – volume: 116 start-page: 497 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib28 article-title: The Wisconsin Epidemiologic Study of diabetic retinopathy XXIII: the twenty-five-year incidence of macular edema in persons with type 1 diabetes publication-title: Ophthalmology doi: 10.1016/j.ophtha.2008.10.016 – volume: 370 start-page: 204 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib139 article-title: Clinical update: new treatments for age-related macular degeneration publication-title: Lancet doi: 10.1016/S0140-6736(07)61104-0 – volume: 23 start-page: 1496 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib48 article-title: Microvascular lesions of diabetic retinopathy: clues towards understanding pathogenesis? publication-title: Eye doi: 10.1038/eye.2009.108 – volume: 49 start-page: 732 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib70 article-title: Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.07-0721 – volume: 6 start-page: 428 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib96 article-title: Accuracy of primary care clinicians in screening for diabetic retinopathy using single-image retinal photography publication-title: Ann Fam Med doi: 10.1370/afm.857 – volume: 13 start-page: 181 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib56 article-title: Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation publication-title: Nat Med doi: 10.1038/nm1534 – volume: 52 start-page: 180 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib40 article-title: Obesity and Eye Diseases publication-title: Survey of Ophthalmology doi: 10.1016/j.survophthal.2006.12.003 – volume: 45 start-page: 269 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib123 article-title: Ruboxistaurin mesilate hydrate for diabetic retinopathy publication-title: Drugs Today (Barc) doi: 10.1358/dot.2009.045.004.1354195 – volume: 14 start-page: 25 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib76 article-title: Arteriolar involvement in the microvascular lesions of diabetic retinopathy: implications for pathogenesis publication-title: Microcirculation doi: 10.1080/10739680601072123 – volume: 88 start-page: 583 year: 1981 ident: 10.1016/S0140-6736(09)62124-3_bib91 article-title: Photocoagulation treatment of proliferative diabetic retinopathy. Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS Report Number 8 publication-title: Ophthalmology doi: 10.1016/S0161-6420(81)34978-1 – volume: 27 start-page: 45 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib97 article-title: State-of-the-art retinal optical coherence tomography publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2007.07.005 – volume: 102 start-page: 7 year: 1995 ident: 10.1016/S0140-6736(09)62124-3_bib27 article-title: The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XV. The long-term incidence of macular edema publication-title: Ophthalmology doi: 10.1016/S0161-6420(95)31052-4 – volume: 13 start-page: 1034 year: 1990 ident: 10.1016/S0140-6736(09)62124-3_bib34 article-title: Is menarche associated with diabetic retinopathy? publication-title: Diabetes Care doi: 10.2337/diacare.13.10.1034 – volume: 116 start-page: 902 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib54 article-title: Intravitreal triamcinolone acetonide injection for treatment of refractory diabetic macular edema: a systematic review publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.02.002 – volume: 50 start-page: 2263 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib80 article-title: The relationship of retinal vascular calibre to diabetes and retinopathy: the Australian Diabetes, Obesity and Lifestyle (AusDiab) study publication-title: Diabetologia doi: 10.1007/s00125-007-0822-x – volume: 117 start-page: 1087 year: 2010 ident: 10.1016/S0140-6736(09)62124-3_bib134 article-title: Diabetic Retinopathy Clinical Research Network Writing Committee on behalf of the DRCR.net. Vitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.10.040 – volume: 115 start-page: 1857 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib26 article-title: From a population to patients: the Wisconsin epidemiologic study of diabetic retinopathy publication-title: Ophthalmology doi: 10.1016/j.ophtha.2008.09.023 – volume: 53 start-page: 512 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib41 article-title: Alcohol and eye diseases publication-title: Surv Ophthalmol doi: 10.1016/j.survophthal.2008.06.003 – volume: 371 start-page: 736 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib103 article-title: Relation between fasting glucose and retinopathy for diagnosis of diabetes: three population-based cross-sectional studies publication-title: Lancet doi: 10.1016/S0140-6736(08)60343-8 – volume: 31 start-page: 1842 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib74 article-title: Retinal arteriolar dilation predicts retinopathy in adolescents with type 1 diabetes publication-title: Diabetes Care doi: 10.2337/dc08-0189 – volume: 361 start-page: 40 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib118 article-title: Renal and retinal effects of enalapril and losartan in type 1 diabetes publication-title: N Engl J Med doi: 10.1056/NEJMoa0808400 – volume: 247 start-page: 147 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib130 article-title: Physiology of vitreous surgery publication-title: Graefes Arch Clin Exp Ophthalmol doi: 10.1007/s00417-008-0980-7 – volume: 27 start-page: 2540 year: 2004 ident: 10.1016/S0140-6736(09)62124-3_bib2 article-title: Diabetic retinopathy publication-title: Diabetes Care doi: 10.2337/diacare.27.10.2540 – volume: 122 start-page: 76 year: 2004 ident: 10.1016/S0140-6736(09)62124-3_bib77 article-title: The relation of retinal vessel caliber to the incidence and progression of diabetic retinopathy: XIX: the Wisconsin Epidemiologic Study of Diabetic Retinopathy publication-title: Arch Ophthalmol doi: 10.1001/archopht.122.1.76 – volume: 246 start-page: 1519 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib15 article-title: Prevalence and associated factors of diabetic retinopathy. The Beijing Eye Study 2006 publication-title: Graefes Arch Clin Exp Ophthalmol doi: 10.1007/s00417-008-0884-6 – volume: 113 start-page: 1488 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib79 article-title: Retinal vascular caliber in persons with type 2 diabetes: the Wisconsin Epidemiological Study of Diabetic Retinopathy: 20 publication-title: Ophthalmology doi: 10.1016/j.ophtha.2006.03.028 – volume: 331 start-page: 1480 year: 1994 ident: 10.1016/S0140-6736(09)62124-3_bib52 article-title: Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders publication-title: N Engl J Med doi: 10.1056/NEJM199412013312203 – volume: 50 start-page: 444 year: 2001 ident: 10.1016/S0140-6736(09)62124-3_bib110 article-title: Cyclic stretch and hypertension induce retinal expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2: potential mechanisms for exacerbation of diabetic retinopathy by hypertension publication-title: Diabetes doi: 10.2337/diabetes.50.2.444 – volume: 50 start-page: 1329 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib67 article-title: Suppression of retinal neovascularization by erythropoietin siRNA in a mouse model of proliferative retinopathy publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.08-2521 – volume: 26 start-page: 1224 year: 2003 ident: 10.1016/S0140-6736(09)62124-3_bib35 article-title: Do all prepubertal years of diabetes duration contribute equally to diabetes complications? publication-title: Diabetes Care doi: 10.2337/diacare.26.4.1224 – volume: 32 start-page: 1704 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib73 article-title: Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: the multi-ethnic study of atherosclerosis publication-title: Diabetes Care doi: 10.2337/dc09-0102 – volume: 28 start-page: 2252 year: 2005 ident: 10.1016/S0140-6736(09)62124-3_bib66 article-title: Erythropoietin is highly elevated in vitreous fluid of patients with proliferative diabetic retinopathy publication-title: Diabetes Care doi: 10.2337/diacare.28.9.2252 – volume: 359 start-page: 967 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib145 article-title: Targeting intraocular neovascularization and edema–one drop at a time publication-title: N Engl J Med doi: 10.1056/NEJMcibr0804551 – volume: 30 start-page: 2902 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib11 article-title: Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration publication-title: Diabetes Care doi: 10.2337/dc07-0332 – volume: 124 start-page: 87 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib82 article-title: Are inflammatory factors related to retinal vessel caliber? The Beaver Dam Eye Study publication-title: Arch Ophthalmol doi: 10.1001/archopht.124.1.87 – volume: 126 start-page: 1740 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib5 article-title: Projection of diabetic retinopathy and other major eye diseases among people with diabetes mellitus: United States, 2005–2050 publication-title: Arch Ophthalmol doi: 10.1001/archopht.126.12.1740 – volume: 26 start-page: 562 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib128 article-title: Diabetic macular edema associated with glitazone use publication-title: Retina doi: 10.1097/00006982-200605000-00011 – volume: 32 start-page: 2075 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib84 article-title: Flicker light-induced retinal vasodilation in diabetes and diabetic retinopathy publication-title: Diabetes Care doi: 10.2337/dc09-0075 – volume: 116 start-page: 1151 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib137 article-title: Analysis of the effect of intravitreal bevacizumab injection on diabetic macular edema after cataract surgery publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.01.014 – volume: 90 start-page: 506 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib24 article-title: The epidemiology of age related eye diseases in Asia publication-title: Br J Ophthalmol doi: 10.1136/bjo.2005.083733 – volume: 290 start-page: 2057 year: 2003 ident: 10.1016/S0140-6736(09)62124-3_bib1 article-title: Important causes of visual impairment in the world today publication-title: JAMA doi: 10.1001/jama.290.15.2057 – year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib39 article-title: Diabetic retinopathy and nephropathy – volume: 356 start-page: 748 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib140 article-title: Ranibizumab for neovascular age-related macular degeneration publication-title: N Engl J Med – volume: 141 start-page: 446 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib29 article-title: Diabetic retinopathy in a multi-ethnic cohort in the United States publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2005.08.063 – volume: 116 start-page: 1937 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib19 article-title: Changes in visual impairment prevalence by period of diagnosis of diabetes the Wisconsin Epidemiologic Study of Diabetic Retinopathy publication-title: Ophthalmology doi: 10.1016/j.ophtha.2009.03.012 – volume: 49 start-page: 35 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib31 article-title: The role of genetics in susceptibility to diabetic retinopathy publication-title: Int Ophthalmol Clin doi: 10.1097/IIO.0b013e31819fd5d7 – volume: 32 start-page: 106 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib87 article-title: Quantitative assessment of early diabetic retinopathy using fractal analysis publication-title: Diabetes Care doi: 10.2337/dc08-1233 – volume: 31 start-page: 1905 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib3 article-title: Ocular associations of diabetes other than diabetic retinopathy publication-title: Diabetes Care doi: 10.2337/dc08-0342 – volume: 128 start-page: 312 year: 2010 ident: 10.1016/S0140-6736(09)62124-3_bib127 article-title: Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy publication-title: Arch Ophthalmol doi: 10.1001/archophthalmol.2009.310 – volume: 31 start-page: 81 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib22 article-title: Is glycemic control improving in U.S. adults? publication-title: Diabetes Care doi: 10.2337/dc07-1572 – volume: 338 start-page: 1425 year: 1991 ident: 10.1016/S0140-6736(09)62124-3_bib86 article-title: Fractals and medicine publication-title: Lancet doi: 10.1016/0140-6736(91)92726-I – volume: 117 start-page: 1067 year: 2010 ident: 10.1016/S0140-6736(09)62124-3_bib135 article-title: Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema publication-title: Ophthalmology – volume: 118 start-page: 2337 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib147 article-title: Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits publication-title: J Clin Invest – volume: 13 start-page: 131 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib65 article-title: A prize catch for diabetic retinopathy publication-title: Nat Med doi: 10.1038/nm0207-131 – volume: 89 start-page: 229 year: 2005 ident: 10.1016/S0140-6736(09)62124-3_bib93 article-title: Why cotton wool spots should not be regarded as retinal nerve fibre layer infarcts publication-title: Br J Ophthalmol doi: 10.1136/bjo.2004.058347 – volume: 370 start-page: 829 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib114 article-title: Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial publication-title: Lancet doi: 10.1016/S0140-6736(07)61303-8 – volume: 347 start-page: 1968 year: 2002 ident: 10.1016/S0140-6736(09)62124-3_bib69 article-title: Erythropoietin—an endogenous retinal survival factor publication-title: N Engl J Med doi: 10.1056/NEJMcibr022629 – volume: 13 start-page: 34 year: 1990 ident: 10.1016/S0140-6736(09)62124-3_bib38 article-title: Effect of pregnancy on progression of diabetic retinopathy publication-title: Diabetes Care doi: 10.2337/diacare.13.1.34 – volume: 122 start-page: 552 year: 2004 ident: 10.1016/S0140-6736(09)62124-3_bib8 article-title: The prevalence of diabetic retinopathy among adults in the United States publication-title: Arch Ophthalmol doi: 10.1001/archopht.122.4.552 – volume: 361 start-page: 195 year: 2003 ident: 10.1016/S0140-6736(09)62124-3_bib98 article-title: Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study publication-title: Lancet doi: 10.1016/S0140-6736(03)12267-2 – volume: 342 start-page: 381 year: 2000 ident: 10.1016/S0140-6736(09)62124-3_bib109 article-title: Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy publication-title: N Engl J Med doi: 10.1056/NEJM200002103420603 – volume: 115 start-page: 1869 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib14 article-title: Prevalence and risk factors for diabetic retinopathy: the Singapore Malay Eye Study publication-title: Ophthalmology doi: 10.1016/j.ophtha.2008.05.014 – volume: 58 start-page: 2137 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib32 article-title: A systematic meta-analysis of genetic association studies for diabetic retinopathy publication-title: Diabetes doi: 10.2337/db09-0059 – volume: 23 start-page: 1084 year: 2000 ident: 10.1016/S0140-6736(09)62124-3_bib37 article-title: Effect of pregnancy on microvascular complications in the diabetes control and complications trial publication-title: Diabetes Care doi: 10.2337/diacare.23.8.1084 – volume: 27 start-page: 608 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib64 article-title: Vascular endothelial growth factor and diabetic complications publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2008.09.002 – volume: 147 start-page: 291 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib143 article-title: Combined laser and intravitreal triamcinolone for proliferative diabetic retinopathy and macular edema: one-year results of a randomized clinical trial publication-title: Am J Ophthalmol doi: 10.1016/j.ajo.2008.08.024 – volume: 126 start-page: 1548 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib18 article-title: Changes in incidence of diabetes mellitus-related eye disease among US elderly persons, 1994–2005 publication-title: Arch Ophthalmol doi: 10.1001/archopht.126.11.1548 – volume: 18 start-page: 160 year: 2004 ident: 10.1016/S0140-6736(09)62124-3_bib36 article-title: The significance of the prepubertal diabetes duration for the development of retinopathy and nephropathy in patients with type 1 diabetes publication-title: J Diabetes Complications doi: 10.1016/S1056-8727(03)00073-4 – volume: 13 start-page: 675 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib61 article-title: Emerging drugs for diabetic retinopathy publication-title: Expert Opin Emerg Drugs doi: 10.1517/14728210802584035 – volume: 12 start-page: 34 issue: suppl 1 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib108 article-title: Insights from the diabetes control and complications trial/epidemiology of diabetes interventions and complications study on the use of intensive glycemic treatment to reduce the risk of complications of type 1 diabetes publication-title: Endocr Pract doi: 10.4158/EP.12.S1.34 – volume: 59 start-page: 1244 year: 2010 ident: 10.1016/S0140-6736(09)62124-3_bib102 article-title: Effect of prior intensive therapy in type 1 diabetes mellitus on 10-year progression of retinopathy in the DCCT/EDIC: comparison of adults and adolescents publication-title: Diabetes doi: 10.2337/db09-1216 – volume: 116 start-page: 461 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib13 article-title: Prevalence of diabetic retinopathy in rural China: the Handan Eye Study publication-title: Ophthalmology doi: 10.1016/j.ophtha.2008.10.003 – volume: 50 start-page: 1 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib124 article-title: Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.08-2473 – volume: 45 start-page: 910 year: 2004 ident: 10.1016/S0140-6736(09)62124-3_bib119 article-title: Diabetic retinopathy and serum lipoprotein subclasses in the DCCT/EDIC cohort publication-title: Invest Ophthalmol Vis Sci doi: 10.1167/iovs.02-0648 – volume: 114 start-page: 881 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib133 article-title: Analysis of macular edema after cataract surgery in patients with diabetes using optical coherence tomography publication-title: Ophthalmology doi: 10.1016/j.ophtha.2006.08.053 – volume: 113 start-page: 1144 year: 1995 ident: 10.1016/S0140-6736(09)62124-3_bib92 article-title: Focal photocoagulation treatment of diabetic macular edema. Relationship of treatment effect to fluorescein angiographic and other retinal characteristics at baseline: ETDRS report no. 19 publication-title: Arch Ophthalmol doi: 10.1001/archopht.1995.01100090070025 – volume: 31 start-page: 544 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib78 article-title: Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi-Ethnic Study of Atherosclerosis (MESA) publication-title: Diabetes Care doi: 10.2337/dc07-1528 – volume: 115 start-page: 1447 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib129 article-title: A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema publication-title: Ophthalmology doi: 10.1016/j.ophtha.2008.06.015 – volume: 103 start-page: 1644 year: 1985 ident: 10.1016/S0140-6736(09)62124-3_bib131 article-title: Early vitrectomy for severe vitreous hemorrhage in diabetic retinopathy. Two-year results of a randomized trial. Diabetic Retinopathy Vitrectomy Study report 2 publication-title: Arch Ophthalmol doi: 10.1001/archopht.1985.01050110038020 – volume: 31 start-page: 708 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib30 article-title: Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes: baseline results from the ADVANCE Retinal Measurements (AdRem) study publication-title: Diabetes Care doi: 10.2337/dc07-1657 – volume: 31 start-page: 761 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib10 article-title: Retinal arteriolar caliber predicts incident retinopathy: the Australia Diabetes, Obesity and Lifestyle (AusDiab) Study publication-title: Diabetes Care doi: 10.2337/dc07-1622 – volume: 27 start-page: 161 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib6 article-title: Diabetic retinopathy and systemic vascular complications publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2007.12.001 – volume: 24 start-page: 32 year: 2004 ident: 10.1016/S0140-6736(09)62124-3_bib63 article-title: Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy publication-title: Am J Nephrol doi: 10.1159/000075627 – volume: 353 start-page: 782 year: 2005 ident: 10.1016/S0140-6736(09)62124-3_bib55 article-title: Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy publication-title: N Engl J Med doi: 10.1056/NEJMoa041773 – volume: 116 start-page: 874 year: 1998 ident: 10.1016/S0140-6736(09)62124-3_bib100 article-title: Early worsening of diabetic retinopathy in the Diabetes Control and Complications Trial publication-title: Arch Ophthalmol doi: 10.1001/archopht.116.7.874 – volume: 360 start-page: 129 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib107 article-title: Glucose control and vascular complications in veterans with type 2 diabetes publication-title: N Engl J Med doi: 10.1056/NEJMoa0808431 – volume: 301 start-page: 2129 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib23 article-title: Diabetes in Asia: epidemiology, risk factors, and pathophysiology publication-title: JAMA doi: 10.1001/jama.2009.726 – volume: 46 start-page: 1829 year: 1997 ident: 10.1016/S0140-6736(09)62124-3_bib33 article-title: Clustering of long-term complications in families with diabetes in the diabetes control and complications trial publication-title: Diabetes doi: 10.2337/diab.46.11.1829 – volume: 51 start-page: 1573 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib47 article-title: Diabetic retinopathy and risk of heart failure publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2007.11.076 – volume: 110 start-page: 1677 year: 2003 ident: 10.1016/S0140-6736(09)62124-3_bib94 article-title: Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales publication-title: Ophthalmology doi: 10.1016/S0161-6420(03)00475-5 – volume: 23 start-page: 73 issue: suppl 1 year: 2000 ident: 10.1016/S0140-6736(09)62124-3_bib99 article-title: Diabetic retinopathy publication-title: Diabetes Care – volume: 113 start-page: 2221 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib59 article-title: Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy publication-title: Ophthalmology doi: 10.1016/j.ophtha.2006.07.032 – volume: 28 start-page: 348 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib72 article-title: Para-inflammation in the aging retina publication-title: Prog Retin Eye Res doi: 10.1016/j.preteyeres.2009.06.001 – volume: 54 start-page: 3103 year: 2005 ident: 10.1016/S0140-6736(09)62124-3_bib125 publication-title: Diabetes doi: 10.2337/diabetes.54.11.3103 – volume: 34 start-page: 748 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib144 article-title: Potential application of adult stem cells in retinal repair–challenge for regenerative medicine publication-title: Curr Eye Res doi: 10.1080/02713680903050592 – volume: 144 start-page: 465 year: 2006 ident: 10.1016/S0140-6736(09)62124-3_bib21 article-title: Improvements in diabetes processes of care and intermediate outcomes: United States, 1988–2002 publication-title: Ann Intern Med doi: 10.7326/0003-4819-144-7-200604040-00005 – volume: 351 start-page: 28 year: 1998 ident: 10.1016/S0140-6736(09)62124-3_bib113 article-title: Effect of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes. The EUCLID Study Group publication-title: Lancet doi: 10.1016/S0140-6736(97)06209-0 – volume: 126 start-page: 1707 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib101 article-title: Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial publication-title: Arch Ophthalmol doi: 10.1001/archopht.126.12.1707 – volume: 359 start-page: 1565 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib112 article-title: Long-term follow-up after tight control of blood pressure in type 2 diabetes publication-title: N Engl J Med doi: 10.1056/NEJMoa0806359 – volume: 116 start-page: 311 year: 2009 ident: 10.1016/S0140-6736(09)62124-3_bib17 article-title: Prevalence of diabetic retinopathy in India: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study report 2 publication-title: Ophthalmology doi: 10.1016/j.ophtha.2008.09.010 – volume: 98 start-page: 766 year: 1991 ident: 10.1016/S0140-6736(09)62124-3_bib90 article-title: Early photocoagulation for diabetic retinopathy. ETDRS report number 9 publication-title: Ophthalmology doi: 10.1016/S0161-6420(13)38011-7 – volume: 95 start-page: 1307 year: 1988 ident: 10.1016/S0140-6736(09)62124-3_bib132 article-title: Early vitrectomy for severe proliferative diabetic retinopathy in eyes with useful vision. Results of a randomized trial–Diabetic Retinopathy Vitrectomy Study Report 3 publication-title: Ophthalmology doi: 10.1016/S0161-6420(88)33015-0 – volume: 114 start-page: 2098 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib75 article-title: Diabetic retinopathy publication-title: Ophthalmology doi: 10.1016/j.ophtha.2007.07.010 – volume: 30 start-page: 3048 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib88 article-title: Influence of flickering light on the retinal vessels in diabetic patients publication-title: Diabetes Care doi: 10.2337/dc07-0927 – volume: 370 start-page: 1687 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib120 article-title: Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial publication-title: Lancet doi: 10.1016/S0140-6736(07)61607-9 – volume: 371 start-page: 721 year: 2008 ident: 10.1016/S0140-6736(09)62124-3_bib121 article-title: Fenofibrate and diabetic retinopathy publication-title: Lancet doi: 10.1016/S0140-6736(08)60333-5 – volume: 125 start-page: 318 year: 2007 ident: 10.1016/S0140-6736(09)62124-3_bib60 article-title: Effect of ruboxistaurin in patients with diabetic macular edema: thirty-month results of the randomized PKC-DMES clinical trial publication-title: Arch Ophthalmol doi: 10.1001/archopht.125.3.318
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Snippet	Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in working-aged... Summary Diabetic retinopathy is a common and specific microvascular complication of diabetes, and remains the leading cause of preventable blindness in...
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SubjectTerms	Angiogenesis Biological and medical sciences Blindness Blood pressure Cardiovascular diseases Clinical trials Coronary heart disease Diabetes Diabetes mellitus Diabetes. Impaired glucose tolerance Diabetic retinopathy Diabetic Retinopathy - diagnosis Diabetic Retinopathy - physiopathology Diabetic Retinopathy - therapy Edema Endocrine pancreas. Apud cells (diseases) Endocrinopathies Epidemiology Etiopathogenesis. Screening. Investigations. Target tissue resistance General aspects Glucose Heart diseases Humans Hypothyroidism Industrialized nations Internal Medicine Lasers Lipids Medical sciences Microvasculature Older people Ophthalmology Pregnancy Preservation Retina Retinopathies Retinopathy Risk Factors Rural areas Steroid hormones Stroke Studies Surgery
Title	Diabetic retinopathy
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