Peripheral vascular disease assessment in the lower limb: a review of current and emerging non-invasive diagnostic methods

Background Worldwide, at least 200 million people are affected by peripheral vascular diseases (PVDs), including peripheral arterial disease (PAD), chronic venous insufficiency (CVI) and deep vein thrombosis (DVT). The high prevalence and serious consequences of PVDs have led to the development of s...

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Published in:Biomedical engineering online Vol. 17; no. 1; pp. 61 - 27
Main Authors: Shabani Varaki, Elham, Gargiulo, Gaetano D., Penkala, Stefania, Breen, Paul P.
Format: Journal Article
Language:English
Published: London BioMed Central 11.05.2018
BioMed Central Ltd
BMC
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ISSN:1475-925X, 1475-925X
Online Access:Get full text
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Summary:Background Worldwide, at least 200 million people are affected by peripheral vascular diseases (PVDs), including peripheral arterial disease (PAD), chronic venous insufficiency (CVI) and deep vein thrombosis (DVT). The high prevalence and serious consequences of PVDs have led to the development of several diagnostic tools and clinical guidelines to assist timely diagnosis and patient management. Given the increasing number of diagnostic methods available, a comprehensive review of available technologies is timely in order to understand their limitations and direct future development effort. Main body This paper reviews the available diagnostic methods for PAD, CVI, and DVT with a focus on non-invasive modalities. Each method is critically evaluated in terms of sensitivity, specificity, accuracy, ease of use, procedure time duration, and training requirements where applicable. Conclusion This review emphasizes the limitations of existing methods, highlighting a latent need for the development of new non-invasive, efficient diagnostic methods. Some newly emerging technologies are identified, in particular wearable sensors, which demonstrate considerable potential to address the need for simple, cost-effective, accurate and timely diagnosis of PVDs.
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ISSN:1475-925X
1475-925X
DOI:10.1186/s12938-018-0494-4