Optical coherence tomography (OCT) - versus angiography-guided strategy for percutaneous coronary intervention: a meta-analysis of randomized trials

Background Optical coherence tomography (OCT) guidance in percutaneous coronary intervention (PCI) has been shown to improve procedural outcomes. However, evidence supporting its superiority over angiography-guided PCI in terms of clinical outcomes is still emerging and limited. This study aimed to...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	BMC cardiovascular disorders Ročník 24; číslo 1; s. 262 - 10
Hlavní autoři:	Wang, Yanwei, Yang, Xi, Wu, Yutao, Li, Yanqin, Zhou, Yijiang
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London BioMed Central 20.05.2024 BioMed Central Ltd Springer Nature B.V BMC
Témata:	Acute coronary syndromes Aged Angiography Angiology Angioplasty Bias Blood Transfusion Medicine Cardiac Surgery Cardiology Care and treatment Clinical trials Collaboration Comparative analysis Coronary Angiography Coronary artery disease Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - mortality Coronary Artery Disease - therapy Coronary heart disease Coronary Thrombosis - diagnostic imaging Coronary Thrombosis - etiology Coronary Vessels - diagnostic imaging Death Female Heart attacks Heart diseases Humans Implants Internal Medicine Male Medical imaging Medicine Medicine & Public Health Meta-analysis Methods Middle Aged Mortality Myocardial infarction Optical coherence tomography Patient outcomes Percutaneous coronary intervention Percutaneous Coronary Intervention - adverse effects Percutaneous Coronary Intervention - instrumentation Percutaneous Coronary Intervention - mortality Predictive Value of Tests Randomized Controlled Trials as Topic Risk Factors Sensitivity analysis Stents Thrombosis Tomography Tomography, Optical Coherence Treatment Outcome China Coronary angiography Percutaneous coronary intervention Optical coherence tomography Coronary artery disease
ISSN:	1471-2261, 1471-2261
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Popis
Shrnutí:	Background Optical coherence tomography (OCT) guidance in percutaneous coronary intervention (PCI) has been shown to improve procedural outcomes. However, evidence supporting its superiority over angiography-guided PCI in terms of clinical outcomes is still emerging and limited. This study aimed to compare the efficacy and safety of OCT-guided PCI versus angiography‐guided PCI in patients with coronary artery disease (CAD). Methods A systematic search of electronic databases was conducted to identify randomized control trials (RCTs) comparing the clinical outcomes of OCT-guided and angiography‐guided PCI in patients with CAD. Clinical endpoints including all-cause mortality, myocardial infarction (MI), target lesion revascularization (TLR), stent thrombosis and major adverse cardiac events (MACE) were assessed. Results Eleven RCTs, comprising 2,699 patients in the OCT-guided group and 2,968 patients in the angiography-guided group met inclusion criteria. OCT-guided PCI was associated with significantly lower rates of cardiovascular death(RR 0.56; 95%CI: 0.32–0.98; p = 0.04; I 2 = 0%), stent thrombosis(RR 0.56; 95%CI: 0.33–0.95; p = 0.03; I 2 = 0%), and MACE (RR 0.79; 95%CI: 0.66–0.95; p = 0.01; I 2 = 5%). The incidence of all-cause death (RR 0.71; 95%CI: 0.49–1.02; p = 0.06; I 2 = 0%), myocardial infarction (RR 0.86; 95%CI: 0.67–1.10; p = 0.22; I 2 = 0%) and TLR (RR 0.98; 95%CI: 0.73–1.33; p = 0.91; I 2 = 0%) was non-significantly lower in the OCT-guided group. Conclusions Among patients undergoing PCI, OCT-guided PCI was associated with lower incidences of cardiovascular death, stent thrombosis and MACE compared to angiography-guided PCI. Trial registration PROSPERO registration number: CRD42023484342.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Article-2 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3
ISSN:	1471-2261 1471-2261
DOI:	10.1186/s12872-024-03930-y