Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study

Background The role of site of infection in sepsis has been poorly characterized. Additionally, sepsis epidemiology has evolved. Early mortality has decreased, but many survivors now progress into chronic critical illness (CCI). This study sought to determine if there were significant differences in...

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Bibliographic Details
Published in:	Critical care (London, England) Vol. 24; no. 1; pp. 203 - 14
Main Authors:	Stortz, Julie A., Cox, Michael C., Hawkins, Russell B., Ghita, Gabriela L., Brumback, Babette A., Mohr, Alicia M., Moldawer, Lyle L., Efron, Philip A., Brakenridge, Scott C., Moore, Frederick A.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 07.05.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Abdomen Activities of daily living Aged Chronic critical illness Clinical trials Cohort Studies Comorbidity Critical care Critical Care Medicine Critical Illness - epidemiology Cross infection Disability Emergency Medicine Epidemiology Female Health aspects Heterogeneity Hospital Mortality - trends Hospital patients Hospitals Humans Hypotheses Illnesses Immunotherapy Infections Intensive Intensive care Long-term outcomes Longitudinal Studies Male Medical records Medical research Medicine Medicine & Public Health Middle Aged Mortality Patients Phenotype Phenotypes Pneumonia Postoperative Complications - etiology Prospective Studies Risk Factors Sepsis Sepsis - classification Sepsis - etiology Site of infection Surgery Surgical sepsis Surgical Wound Infection - classification Surgical Wound Infection - complications Trauma Ventilators Viral infections United States > US Heterogeneity Phenotypes Immunosuppression Chronic critical illness Proinflammation Functional outcomes Long-term outcomes Site of infection Organ dysfunction Surgical sepsis
ISSN:	1364-8535, 1466-609X, 1364-8535, 1466-609X, 1366-609X
Online Access:	Get full text
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