An epigenome-wide association study of metabolic syndrome and its components

The role of metabolic syndrome (MetS) as a preceding metabolic state for type 2 diabetes and cardiovascular disease is widely recognised. To accumulate knowledge of the pathological mechanisms behind the condition at the methylation level, we conducted an epigenome-wide association study (EWAS) of M...

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Bibliographic Details
Published in:	Scientific reports Vol. 10; no. 1; pp. 20567 - 12
Main Authors:	Nuotio, Marja-Liisa, Pervjakova, Natalia, Joensuu, Anni, Karhunen, Ville, Hiekkalinna, Tero, Milani, Lili, Kettunen, Johannes, Järvelin, Marjo-Riitta, Jousilahti, Pekka, Metspalu, Andres, Salomaa, Veikko, Kristiansson, Kati, Perola, Markus
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 25.11.2020 Nature Publishing Group Nature Portfolio
Subjects:	631/208/176/1988 692/308/2056 Adult Aged ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics Cardiovascular diseases Carrier Proteins - genetics Chromosome 1 Chromosome 21 Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - genetics DNA methylation DNA Methylation - genetics Epigenesis, Genetic - genetics Epigenome - genetics Epigenomics - methods Female Finland - epidemiology Genome - genetics Genome-Wide Association Study - methods Genomes Glucose Glucose - metabolism High density lipoprotein Humanities and Social Sciences Humans Lipid metabolism Lipid Metabolism - genetics Lipids - genetics Male Metabolic disorders Metabolic syndrome Metabolic Syndrome - genetics Metabolic Syndrome - metabolism Methylation Middle Aged multidisciplinary Polymorphism, Single Nucleotide - genetics Science Science (multidisciplinary) Triglycerides White People - genetics Finland
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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