Genetic regulation of gene expression and splicing during a 10-year period of human aging

Background Molecular and cellular changes are intrinsic to aging and age-related diseases. Prior cross-sectional studies have investigated the combined effects of age and genetics on gene expression and alternative splicing; however, there has been no long-term, longitudinal characterization of thes...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genome Biology Jg. 20; H. 1; S. 230
Hauptverfasser:	Balliu, Brunilda, Durrant, Matthew, Goede, Olivia de, Abell, Nathan, Li, Xin, Liu, Boxiang, Gloudemans, Michael J., Cook, Naomi L., Smith, Kevin S., Knowles, David A., Pala, Mauro, Cucca, Francesco, Schlessinger, David, Jaiswal, Siddhartha, Sabatti, Chiara, Lind, Lars, Ingelsson, Erik, Montgomery, Stephen B.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 04.11.2019 Springer Nature B.V BMC
Schlagworte:	Age Aged Aged, 80 and over Aging Aging - genetics Aging - metabolism Alternative Splicing Animal Genetics and Genomics Bioinformatics Biomedical and Life Sciences blood Blood pressure Cholesterol Disease Evolutionary Biology Female Gene expression Gene Expression Regulation Gene regulation genome Human Genetics Humans Life Sciences Longevity Longitudinal studies Male Metabolism Microbial Genetics and Genomics Plant Genetics and Genomics RNA transcriptome Transcriptomes variance Aging Alternative splicing Longevity Gene expression Gene regulation
ISSN:	1474-760X, 1474-7596, 1465-6906, 1474-760X
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!