Diagnosis of central disorders of hypersomnolence: A reappraisal by European experts

The aim of this European initiative is to facilitate a structured discussion to improve the next edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter on central disorders of hypersomnolence. The ultimate goal for a sleep disorders classification is to be ba...

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Vydané v:Sleep medicine reviews Ročník 52; s. 101306
Hlavní autori: Lammers, Gert Jan, Bassetti, Claudio L.A., Dolenc-Groselj, Leja, Jennum, Poul J., Kallweit, Ulf, Khatami, Ramin, Lecendreux, Michel, Manconi, Mauro, Mayer, Geert, Partinen, Markku, Plazzi, Giuseppe, Reading, Paul J., Santamaria, Joan, Sonka, Karel, Dauvilliers, Yves
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: England Elsevier Ltd 01.08.2020
Elsevier
Predmet:
Cataplexy
Classification
Diagnosis
Excessive daytime sleepiness
Fatigue
Hypersomnia
Hypersomnolence
Life Sciences
MSLT
Narcolepsy
Neurology
Sleep
Sleep inertia
Sleep Medicine
Hypersomnia
Sleep
Classification
Excessive daytime sleepiness
Fatigue
Narcolepsy
MSLT
Diagnosis
Hypersomnolence
Sleep inertia
Cataplexy
ISSN:1087-0792, 1532-2955, 1532-2955
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Shrnutí:The aim of this European initiative is to facilitate a structured discussion to improve the next edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter on central disorders of hypersomnolence. The ultimate goal for a sleep disorders classification is to be based on the underlying neurobiological causes of the disorders with clear implication for treatment or, ideally, prevention and or healing. The current ICSD classification, published in 2014, inevitably has important shortcomings, largely reflecting the lack of knowledge about the precise neurobiological mechanisms underlying the majority of sleep disorders we currently delineate. Despite a clear rationale for the present structure, there remain important limitations that make it difficult to apply in routine clinical practice. Moreover, there are indications that the current structure may even prevent us from gaining relevant new knowledge to better understand certain sleep disorders and their neurobiological causes. We suggest the creation of a new consistent, complaint driven, hierarchical classification for central disorders of hypersomnolence; containing levels of certainty, and giving diagnostic tests, particularly the MSLT, a weighting based on its specificity and sensitivity in the diagnostic context. We propose and define three diagnostic categories (with levels of certainty): 1/“Narcolepsy” 2/“Idiopathic hypersomnia”, 3/“Idiopathic excessive sleepiness” (with subtypes).
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Review-3
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ISSN:1087-0792
1532-2955
1532-2955
DOI:10.1016/j.smrv.2020.101306