Characterization of the phenotypic consequences of the Duffy-null genotype

•rs2814778-CC is only reproducibly associated with changes in white blood cell count and not with any disease outcomes.•Race is not an accurate predictor of Duffy-null–associated benign neutropenia; genetic screening of rs2814778 is needed. [Display omitted] A wealth of research focused on African A...

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Veröffentlicht in:	Blood advances Jg. 9; H. 6; S. 1452 - 1462
Hauptverfasser:	Hysong, Micah R., Shuey, Megan M., Huffman, Jennifer E., Auer, Paul, Reiner, Alexander, Raffield, Laura M.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 25.03.2025 The American Society of Hematology Elsevier
Schlagworte:	Duffy Blood-Group System - genetics Genotype Humans Leukocyte Count Neutropenia - genetics Phagocytes, Granulocytes, and Myelopoiesis Phenotype Polymorphism, Single Nucleotide Receptors, Cell Surface - genetics
ISSN:	2473-9529, 2473-9537, 2473-9537
Online-Zugang:	Volltext
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