Hyperphosphorylated tau in young and middle-aged subjects

The brain tissue obtained from ninety-five cognitively unimpaired subjects, with ages ranging from 22 to 50 years upon death, were immunohistochemically assessed for neurodegenerative changes, i.e., hyperphosphorylated tau (HPτ) and β-amyloid (Aβ) pathology in predilection neuroanatomical areas. HPτ...

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Veröffentlicht in:	Acta neuropathologica Jg. 123; H. 1; S. 97 - 104
Hauptverfasser:	Elobeid, Adila, Soininen, Hilkka, Alafuzoff, Irina
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Berlin/Heidelberg Springer-Verlag 01.01.2012 Springer Springer Nature B.V
Schlagworte:	Adult Age Age Factors Aging Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer's disease Amyloid beta-Peptides - metabolism Anatomy beta -Amyloid Brain Brain - metabolism Brain - pathology Brain architecture Cognitive ability Cognitively unimpaired Cortex Emotional disorders Female Geriatrics Humans Hyperphosphorylated tau Immunohistochemistry Locus coeruleus Male Medical research Medicine Medicine & Public Health Medicine, Experimental Microtubule-associated proteins Middle age Middle Aged Mood Mood disorders Neurodegeneration Neuropathology Neurosciences Original Paper Pathology Phosphorylation - physiology Post-mortem study Risk factors Tau protein tau Proteins - metabolism Finland Immunohistochemistry Hyperphosphorylated tau Middle-aged Post-mortem study Locus coeruleus Cognitively unimpaired
ISSN:	0001-6322, 1432-0533, 1432-0533
Online-Zugang:	Volltext
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