Secular changes in the age-specific prevalence of diabetes among U.S. adults: 1988-2010

To examine the age-specific changes of prevalence of diabetes among U.S. adults during the past 2 decades. This study included 22,586 adults sampled in three periods of the National Health and Nutrition Examination Survey (1988-1994, 1999-2004, and 2005-2010). Diabetes was defined as having self-rep...

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Veröffentlicht in:Diabetes care Jg. 36; H. 9; S. 2690
Hauptverfasser: Cheng, Yiling J, Imperatore, Giuseppina, Geiss, Linda S, Wang, Jing, Saydah, Sharon H, Cowie, Catherine C, Gregg, Edward W
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 01.09.2013
Schlagworte:
Adult
Age Distribution
Age Factors
Aged
Body Composition - physiology
Body Mass Index
Diabetes Mellitus, Type 2 - epidemiology
Female
Humans
Male
Middle Aged
Obesity - epidemiology
Prevalence
Waist Circumference
Young Adult
ISSN:1935-5548, 1935-5548
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Zusammenfassung:To examine the age-specific changes of prevalence of diabetes among U.S. adults during the past 2 decades. This study included 22,586 adults sampled in three periods of the National Health and Nutrition Examination Survey (1988-1994, 1999-2004, and 2005-2010). Diabetes was defined as having self-reported diagnosed diabetes or having a fasting plasma glucose level ≥ 126 mg/dL or HbA1c ≥ 6.5% (48 mmol/mol). The number of adults with diabetes increased by 75% from 1988-1994 to 2005-2010. After adjusting for sex, race/ethnicity, and education level, the prevalence of diabetes increased over the two decades across all age-groups. Younger adults (20-34 years of age) had the lowest absolute increase in diabetes prevalence of 1.0%, followed by middle-aged adults (35-64) at 2.7% and older adults (≥ 65) at 10.0% (all P < 0.001). Comparing 2005-2010 with 1988-1994, the adjusted prevalence ratios (PRs) by age-group were 2.3, 1.3, and 1.5 for younger, middle-aged, and older adults, respectively (all P < 0.05). After additional adjustment for body mass index (BMI), waist-to-height ratio (WHtR), or waist circumference (WC), the adjusted PR remained statistically significant only for adults ≥ 65 years of age. During the past two decades, the prevalence of diabetes increased across all age-groups, but adults ≥ 65 years of age experienced the largest increase in absolute change. Obesity, as measured by BMI, WHtR, or WC, was strongly associated with the increase in diabetes prevalence, especially in adults <65.
Bibliographie:ObjectType-Article-1
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ISSN:1935-5548
1935-5548
DOI:10.2337/dc12-2074