Altered morphological dynamics of activated microglia after induction of status epilepticus

Background Microglia cells are the resident macrophages of the central nervous system and are considered its first line of defense. In the normal brain, their ramified processes are highly motile, constantly scanning the surrounding brain tissue and rapidly moving towards sites of acute injury or da...

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Bibliographic Details
Published in:	Journal of neuroinflammation Vol. 12; no. 1; p. 202
Main Authors:	Avignone, Elena, Lepleux, Marilyn, Angibaud, Julie, Nägerl, U. Valentin
Format:	Journal Article
Language:	English
Published:	London BioMed Central 04.11.2015 BioMed Central Ltd Springer Nature B.V
Subjects:	Analysis Animals Biomedical and Life Sciences Biomedicine Care and treatment Cell Movement CX3C Chemokine Receptor 1 Dynamics Epilepsy Excitatory Amino Acid Agonists Hippocampus - pathology Immunology In Vitro Techniques Inflammation - pathology Kainic Acid Macrophage Activation - drug effects Mice Mice, Inbred C57BL Microglia - pathology Neurobiology Neurology Neurosciences Purinergic P2Y Receptor Agonists - pharmacology Receptors, Chemokine - genetics Receptors, Purinergic P2Y12 Risk factors Status Epilepticus - chemically induced Status Epilepticus - pathology Two-photon microscopy Inflammation Laser lesion Microglial dynamics Epilepsy Microglia
ISSN:	1742-2094, 1742-2094
Online Access:	Get full text
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