Feasibility and effect of life skills building education and multiple micronutrient supplements versus the standard of care on anemia among non-pregnant adolescent and young Pakistani women (15–24 years): a prospective, population-based cluster-randomized trial

Background Adolescence is a critical period for physical and psychological growth and development, and vitamin and mineral requirements are correspondingly increased. Health and health behaviours correspond strongly from adolescence to adulthood. Developing a preconception care package for adolescen...

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Bibliographic Details
Published in:Reproductive health Vol. 15; no. 1; pp. 103 - 9
Main Authors: Baxter, Jo-Anna B., Wasan, Yaqub, Soofi, Sajid B., Suhag, Zamir, Bhutta, Zulfiqar A.
Format: Journal Article
Language:English
Published: London BioMed Central 30.05.2018
BioMed Central Ltd
Springer Nature B.V
BMC
Subjects:
Access to education
Adolescence
Adolescent
Adult
Analysis
Anemia
Anemia - epidemiology
Anemia - therapy
Anthropometry
Child development
Childrens health
Clinical trials
Dietary Supplements
Education
Empowerment
Evidence-based medicine
Feasibility Studies
Female
Food and nutrition
Girls
Health aspects
Health care
Health Education
Humans
Iron
Life skills
Life Style
Low income groups
Maternal and Child Health
Medicine
Medicine & Public Health
Micronutrients
Micronutrients - administration & dosage
Nutrition
Preconception
Preconception Care - methods
Pregnancy
Pregnant women
Prospective Studies
Public Health
Reproductive health
Reproductive Medicine
Rural Population
Social psychology
Standard of care
Standard of Care - statistics & numerical data
Study Protocol
Teenagers
Well being
Womens health
Young Adult
Young adults
Youth
Pakistan
Adolescence
Micronutrients
Nutrition
Education
Anemia
Young adult
Preconception
Empowerment
ISSN:1742-4755, 1742-4755
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Summary:Background Adolescence is a critical period for physical and psychological growth and development, and vitamin and mineral requirements are correspondingly increased. Health and health behaviours correspond strongly from adolescence to adulthood. Developing a preconception care package for adolescent and young women in resource-limited settings could serve to empower them to make informed decisions about their nutrition, health, and well-being, as well as function as a platform for the delivery of basic nutrition-related interventions to address undernutrition. Methods In this population-based two-arm, cluster-randomized, controlled trial of life skills building education (provided bi-monthly) and multiple micronutrient supplementation (provided twice-weekly; UNIMMAP composition), we aim to evaluate the effectiveness of the intervention on the prevention of anemia (hemoglobin concentration < 12 g/dL) among adolescent and young women (15–24 years) in Matiari district, Pakistan compared to the standard of care. Several secondary objectives related to nutrition (anthropometry [height, weight, middle upper arm circumference (MUAC)], nutritional status [iron, vitamin A, vitamin D]); general health (morbidity, mortality); and empowerment (age at marriage, completion of the 10th grade, use of personal hygienic materials during menstruation) will also be assessed. Participants will be enrolled in the study for a maximum of 2 years. Discussion Empowering adolescent and young women with the appropriate knowledge to make informed and healthy decisions will be key to sustained behavioural change throughout the life-course. Although multiple micronutrient deficiencies are known to exist among adolescent and young women in low-resource settings, recommendations on preconception multiple micronutrient supplementation do not exist at this time. This study is expected to offer insight into providing an intervention that includes both education and supplements to non-pregnant adolescent and young women for a prolonged duration of time within the existing public health programmatic context. Trial registration This study is part of the Matiari emPowerment and Preconception Supplementation (MaPPS) Trial. The MaPPS Trial was registered retrospectively on clinicaltrials.gov (Identifier: NCT03287882 ) on September 19, 2017.
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ISSN:1742-4755
1742-4755
DOI:10.1186/s12978-018-0547-y