Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all

The currently available arsenal of anticancer modalities includes many DNA damaging agents that can kill malignant cells. However, efficient DNA repair mechanisms protect both healthy and cancer cells against the effects of treatment and contribute to the development of drug resistance. Therefore, a...

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Bibliographic Details
Published in:	Radiation oncology (London, England) Vol. 10; no. 1; p. 165
Main Authors:	Oei, Arlene L., Vriend, Lianne E. M., Crezee, Johannes, Franken, Nicolaas A. P., Krawczyk, Przemek M.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 07.08.2015 BioMed Central Ltd Springer Nature B.V
Subjects:	Animals Antineoplastic Agents - pharmacology Biomedical and Life Sciences Biomedicine Cancer Cancer Research Chemotherapy Clinical Radiation Oncology DNA DNA damage DNA Damage - drug effects DNA Damage - physiology DNA repair DNA Repair - physiology Drug resistance Genetic aspects Health aspects Humans Hyperthermia, Induced Imaging Ionizing radiation Mediation Neoplasms - therapy Oncology Radiology Radiotherapy Chemotherapy Hyperthermia DNA repair DNA damage
ISSN:	1748-717X, 1748-717X
Online Access:	Get full text
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