CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA

Background CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC), displaying aggressive and metastatic phenotype. Using two different in vitro models, already described as CD90+ liver cancer stem cells, our aim was to study their interaction with endothelial cells mediated by t...

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Bibliographic Details
Published in:	Molecular cancer Vol. 14; no. 1; p. 155
Main Authors:	Conigliaro, Alice, Costa, Viviana, Lo Dico, Alessia, Saieva, Laura, Buccheri, Simona, Dieli, Francesco, Manno, Mauro, Raccosta, Samuele, Mancone, Carmine, Tripodi, Marco, De Leo, Giacomo, Alessandro, Riccardo
Format:	Journal Article
Language:	English
Published:	London BioMed Central 14.08.2015 BioMed Central Ltd Springer Nature B.V
Subjects:	Analysis Biomedical and Life Sciences Biomedicine Cancer cells Cancer Research Cell Adhesion Cell Line, Tumor Development and progression Endothelial Cells - metabolism Endothelium Exosomes - metabolism Genetic aspects Human Umbilical Vein Endothelial Cells - metabolism Humans Liver cancer Liver Neoplasms - genetics Liver Neoplasms - metabolism Metastasis Oncology Phenotype Physiological aspects RNA RNA, Long Noncoding - genetics Thy-1 Antigens - metabolism United Kingdom CD90+ liver cancer cells Angiogenesis Long-non-coding RNA H19 Exosomes
ISSN:	1476-4598, 1476-4598
Online Access:	Get full text
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