A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results

Randomized controlled trials (RCTs) are conducted under idealized and rigorously controlled conditions that may compromise their external validity. A literature review was conducted of published English language articles that reported the findings of studies assessing external validity by a comparis...

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Bibliographic Details
Published in:	Current controlled trials in cardiovascular medicine Vol. 16; no. 1; p. 495
Main Authors:	Kennedy-Martin, Tessa, Curtis, Sarah, Faries, Douglas, Robinson, Susan, Johnston, Joseph
Format:	Journal Article
Language:	English
Published:	London BioMed Central 03.11.2015 BioMed Central Ltd Springer Nature B.V
Subjects:	Biomedicine Cardiology Clinical medicine Data Interpretation, Statistical Evidence-based medicine Evidence-Based Medicine - methods Evidence-Based Medicine - statistics & numerical data Health Sciences Humans Internal validity Intervention Literature reviews Medical Oncology Medical research Medicine Medicine & Public Health Mental health Mental Health Services Methods Observational studies Older people Patients Randomized Controlled Trials as Topic - methods Randomized Controlled Trials as Topic - statistics & numerical data Reproducibility of Results Research Design - statistics & numerical data Review Statistics for Life Sciences Treatment Outcome United States Generalizability Mental health Literature review External validity Oncology Real-world patients Cardiology Randomized controlled trial
ISSN:	1745-6215, 1745-6215
Online Access:	Get full text
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