Predictors of poor functional outcomes and mortality in patients with hip fracture: a systematic review

Background Hip fracture is an important and prevalent medical condition associated with adverse outcomes. The aim of this article is to systematically review and summarise the predictors of poor functional outcomes and mortality for patients with hip fractures. Methods We conducted a systemic litera...

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Veröffentlicht in:BMC musculoskeletal disorders Jg. 20; H. 1; S. 568 - 9
Hauptverfasser: Xu, Bang Yu, Yan, Shi, Low, Lian Leng, Vasanwala, Farhad Fakhrudin, Low, Sher Guan
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London BioMed Central 27.11.2019
BioMed Central Ltd
Springer Nature B.V
BMC
Schlagworte:
Activities of Daily Living
Aging
Arthritis
Clinical outcomes
Cognitive ability
Epidemiology
Fractures
Fractures (Injuries)
Frailty
Full text
Functional outcomes
Gait
Hand Strength - physiology
Health care industry
Hip
Hip fractures
Hip Fractures - diagnosis
Hip Fractures - mortality
Hip Fractures - therapy
Humans
Internal Medicine
Medical research
Medical societies
Medicine
Medicine & Public Health
Mortality
Mortality - trends
Muscle function
Musculoskeletal diseases
Older people
Orthopedics
Osteoporosis
Patient outcomes
Patients
physical therapy and occupational health
Predictive Value of Tests
Predictors
Professional associations
Recovery of Function - physiology
Rehabilitation
Research Article
Rheumatology
Sarcopenia
Sports Medicine
Surgery
Systematic review
Treatment Outcome
United Kingdom
Working groups
United Kingdom
Hip fractures
Functional outcomes
Mortality
Predictors
ISSN:1471-2474, 1471-2474
Online-Zugang:Volltext
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Zusammenfassung:Background Hip fracture is an important and prevalent medical condition associated with adverse outcomes. The aim of this article is to systematically review and summarise the predictors of poor functional outcomes and mortality for patients with hip fractures. Methods We conducted a systemic literature search using PubMed, EMBASE and Cochrane Library. We included English peer-reviewed cohort studies that examined predictors of poor functional outcomes (such as independence in Activities of Daily Living) and mortality for patients with hip fracture published in the past 15 years (from 1 Jan 2004 up to 30 May 2019). Two independent researchers evaluated the articles for eligibility. Consensus on the eligibility was sought and a third researcher was involved if there was disagreement. A standardised form was used to extract relevant data. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of the included studies. Results We retrieved 4339 and included 81 articles. We identified two emerging predictors of poor functional outcomes and mortality for patients with hip fractures: low hand grip strength and frailty in line with an emerging concept of “physical performance”. The predictors identified in this systematic review can be grouped into 1) medical factors, such as presence of co-morbidities, high American Society of Anesthesiologists (ASA) grade, sarcopenia, 2) surgical factors including delay in operation (e.g. > 48 h), type of fracture s, 3) socio-economic factors which include age, gender, ethnicity, and 4) system factors including lower case-volume centers. Conclusions This systematic review identified multiple significant predictors of poor functional outcomes and mortality, with the hand grip strength and frailty being important emerging predictors in the most recent literature. These predictors would further inform healthcare providers of their patients’ health status and allow for early intervention for modifiable predictors.
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ISSN:1471-2474
1471-2474
DOI:10.1186/s12891-019-2950-0