Single-Dose Azithromycin versus Penicillin G Benzathine for the Treatment of Early Syphilis

This randomized trial involving patients with early syphilis in Tanzania found that treatment with 2 g of azithromycin led to cure rates that were similar to those for penicillin G benzathine at both nine months (97.7 percent and 95.0 percent, respectively) and six months (85.5 percent and 81.5 perc...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 353; no. 12; pp. 1236 - 1244
Main Authors:	Riedner, Gabriele, Rusizoka, Mary, Todd, Jim, Maboko, Leonard, Hoelscher, Michael, Mmbando, Donan, Samky, Eleuter, Lyamuya, Eligius, Mabey, David, Grosskurth, Heiner, Hayes, Richard
Format:	Journal Article
Language:	English
Published:	Boston, MA Massachusetts Medical Society 22.09.2005
Subjects:	Administration, Oral Adolescent Adult Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Azithromycin - administration & dosage Bacterial diseases Bacterial diseases of the genital system Biological and medical sciences Developing Countries Female General aspects HIV HIV Seropositivity - complications Human bacterial diseases Human immunodeficiency virus Humans Infections Infectious diseases Injections, Intramuscular Male Medical sciences Penicillin Penicillin G Benzathine - administration & dosage Penicillin G Benzathine - therapeutic use Proportional Hazards Models Syphilis - complications Syphilis - drug therapy Treponema pallidum Ulcers β-Lactams Azithromycin Single dose Early stage Macrolide Treponematosis Infection Penicillin derivatives Medicine Antibiotic Sexually transmitted disease Treatment Spirochaetosis Syphilis Bacteriosis Antibacterial agent Benzathine benzylpenicillin Comparative study
ISSN:	0028-4793, 1533-4406, 1533-4406
Online Access:	Get full text
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