Monogenic and polygenic determinants of sarcoma risk: an international genetic study

Sarcomas are rare, phenotypically heterogeneous cancers that disproportionately affect the young. Outside rare syndromes, the nature, extent, and clinical significance of their genetic origins are not known. We aimed to investigate the genetic basis for bone and soft-tissue sarcoma seen in routine c...

Full description

Saved in:

Bibliographic Details
Published in:	The lancet oncology Vol. 17; no. 9; pp. 1261 - 1271
Main Authors:	Ballinger, Mandy L, Goode, David L, Ray-Coquard, Isabelle, James, Paul A, Mitchell, Gillian, Niedermayr, Eveline, Puri, Ajay, Schiffman, Joshua D, Dite, Gillian S, Cipponi, Arcadi, Maki, Robert G, Brohl, Andrew S, Myklebost, Ola, Stratford, Eva W, Lorenz, Susanne, Ahn, Sung-Min, Ahn, Jin-Hee, Kim, Jeong Eun, Shanley, Sue, Beshay, Victoria, Randall, Robert Lor, Judson, Ian, Seddon, Beatrice, Campbell, Ian G, Young, Mary-Anne, Sarin, Rajiv, Blay, Jean-Yves, O'Donoghue, Seán I, Thomas, David M
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.09.2016 Elsevier Limited
Subjects:	Adolescent Adult Age Aged Aged, 80 and over Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Breast cancer Case-Control Studies Cell cycle Child Child, Preschool Classification Disease Exome - genetics Family medical history Female Follow-Up Studies Genes Genetic diversity Genomes Genotype & phenotype Health risk assessment Hematology, Oncology and Palliative Medicine High-Throughput Nucleotide Sequencing - methods Humans Infant Infant, Newborn International Agencies Male Mammography Medical research Middle Aged Mutation Mutation - genetics Neoplasm Staging Pedigree Population Prognosis Risk Factors Saliva Saliva - chemistry Sarcoma Sarcoma - blood Sarcoma - genetics Studies Young Adult
ISSN:	1470-2045, 1474-5488, 1474-5488
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!