A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1

Hongbing Shen, Dongxin Lin, Yongyong Shi and colleagues identify two new susceptibility loci for non-cardia gastric cancer. They also confirm three previously reported risk loci for this gastric cancer subtype. Gastric cancer, including the cardia and non-cardia types, is the second leading cause of...

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Vydáno v:	Nature genetics Ročník 43; číslo 12; s. 1215 - 1218
Hlavní autoři:	Shi, Yongyong, Hu, Zhibin, Wu, Chen, Dai, Juncheng, Li, Huizhang, Dong, Jing, Wang, Meilin, Miao, Xiaoping, Zhou, Yifeng, Lu, Feng, Zhang, Hanze, Hu, Lingmin, Jiang, Yue, Li, Zhiqiang, Chu, Minjie, Ma, Hongxia, Chen, Jiaping, Jin, Guangfu, Tan, Wen, Wu, Tangchun, Zhang, Zhengdong, Lin, Dongxin, Shen, Hongbing
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New York Nature Publishing Group US 01.12.2011 Nature Publishing Group
Témata:	631/208/205/2138 631/208/727/2000 631/67/2324 692/699/67/1504/1829 Adult Aged Agriculture AMP-Activated Protein Kinases - genetics Animal Genetics and Genomics Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Cancer Research Case-Control Studies Chromosomes, Human, Pair 3 - genetics Chromosomes, Human, Pair 5 - genetics Confidence intervals Development and progression Disease susceptibility Female Fundamental and applied biological sciences. Psychology Gastroenterology. Liver. Pancreas. Abdomen Gene Function Genetic aspects Genetic Loci Genetics of eukaryotes. Biological and molecular evolution Genome-Wide Association Study Genomes Health care Human Genetics Humans letter Male Medical sciences Middle Aged Nerve Tissue Proteins - genetics Odds Ratio Pathogenesis Polymorphism, Single Nucleotide Public health R&D Receptors, Prostaglandin E, EP4 Subtype - genetics Research & development Risk factors Sample size Single nucleotide polymorphisms Stomach cancer Stomach Neoplasms - genetics Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Studies Transcription Factors - genetics Tumors China Digestive diseases Identification Malignant tumor Locus Stomach cancer Cancer Gastric disease
ISSN:	1061-4036, 1546-1718, 1546-1718
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