Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes

OBJECTIVE: A loss of skeletal muscle mass is frequently observed in older adults. The aim of the study was to investigate the impact of type 2 diabetes on the changes in body composition, with particular interest in the skeletal muscle mass. RESEARCH DESIGN AND METHODS: We examined total body compos...

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Bibliographic Details
Published in:	Diabetes care Vol. 32; no. 11; pp. 1993 - 1997
Main Authors:	Park, Seok Won, Goodpaster, Bret H, Lee, Jung Sun, Kuller, Lewis H, Boudreau, Robert, de Rekeneire, Nathalie, Harris, Tamara B, Kritchevsky, Stephen, Tylavsky, Frances A, Nevitt, Michael, Cho, Yong-wook, Newman, Anne B
Format:	Journal Article
Language:	English
Published:	Alexandria, VA American Diabetes Association 01.11.2009
Subjects:	Absorptiometry, Photon Adipose Tissue Adipose Tissue - anatomy & histology Age Aged Aging Aging - physiology anatomy & histology Biological and medical sciences blood blood glucose Blood Glucose - metabolism Body Composition Body fat Body Mass Index Body Weight computed tomography Dextrose Diabetes Mellitus, Type 2 Diabetes Mellitus, Type 2 - diagnostic imaging Diabetes Mellitus, Type 2 - pathology Diabetes Mellitus, Type 2 - physiopathology Diabetes. Impaired glucose tolerance dual-energy X-ray absorptiometry elderly Endocrine pancreas. Apud cells (diseases) Endocrinopathies Enzyme-Linked Immunosorbent Assay Etiopathogenesis. Screening. Investigations. Target tissue resistance fasting Female Glucose Glucose Tolerance Test Humans Hypoglycemic agents Hypoglycemic Agents - therapeutic use Interleukin-6 Interleukin-6 - blood Male Medical sciences Metabolic diseases metabolism Middle Aged Miscellaneous Mortality Muscle, Skeletal Muscle, Skeletal - anatomy & histology Muscle, Skeletal - diagnostic imaging Muscle, Skeletal - pathology Muscular system noninsulin-dependent diabetes mellitus Nutrition Older people Organ Size Original Research pathology Physiological aspects physiology physiopathology Public health. Hygiene Public health. Hygiene-occupational medicine radiography Regression Analysis risk Risk factors skeletal muscle Studies therapeutic use Tomography Tumor Necrosis Factor-alpha Tumor Necrosis Factor-alpha - blood Type 2 diabetes Variables women Endocrinopathy Human Type 2 diabetes Mass Nutrition Loss Metabolic diseases Striated muscle Elderly Endocrinology
ISSN:	0149-5992, 1935-5548, 1935-5548
Online Access:	Get full text
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