One chromosome, one contig: complete microbial genomes from long-read sequencing and assembly

•We describe three long-read sequencing technologies and their characteristics.•We describe available algorithms for long-read assembly and their use.•Most microbial genomes can now be automatically finished using long reads.•The total cost of finishing microbial genomes is now under $1000.•New meth...

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Vydané v:	Current opinion in microbiology Ročník 23; s. 110 - 120
Hlavní autori:	Koren, Sergey, Phillippy, Adam M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Elsevier Ltd 01.02.2015
Predmet:	automation Chromosomes Contig Mapping - methods Contig Mapping - trends genome Genome, Microbial Molecular Biology - methods Molecular Biology - trends Pathology Sequence Analysis, DNA - methods Sequence Analysis, DNA - trends
ISSN:	1369-5274, 1879-0364, 1879-0364
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