Characterization of Zika virus binding and enhancement potential of a large panel of flavivirus murine monoclonal antibodies

Zika viruses (ZIKVs) are circulating in parts of the world endemic for other flavivirus infections. Some cross-reactive antibodies (Abs) elicited by prior flavivirus exposures can bind to ZIKV and enhance infection of Fc receptor-bearing cells. Here, we measured ZIKV binding of 54 murine monoclonal...

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Bibliographic Details
Published in:	Virology (New York, N.Y.) Vol. 508; pp. 1 - 6
Main Authors:	Willis, Elinor, Hensley, Scott E.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.08.2017
Subjects:	Animals Antibodies, Monoclonal - immunology Antibodies, Viral - immunology Antibody Antibody mediated enhancement Cross Reactions Dengue virus Flavivirus Flavivirus - immunology Flavivirus Infections - immunology Flavivirus Infections - virology Humans Infectious Disease Mice Viral Envelope Proteins - immunology virology West Nile virus Zika virus Zika Virus - immunology Zika Virus Infection - immunology Zika Virus Infection - virology Zika virus Antibody mediated enhancement Antibody Flavivirus
ISSN:	0042-6822, 1096-0341, 1096-0341
Online Access:	Get full text
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