Characterization of isomeric glycan structures by LC‐MS/MS

The characterization of glycosylation is critical for obtaining a comprehensive view of the regulation and functions of glycoproteins of interest. Due to the complex nature of oligosaccharides, stemming from variable compositions and linkages, and ion suppression effects, the chromatographic separat...

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Bibliographic Details
Published in:	Electrophoresis Vol. 38; no. 17; pp. 2100 - 2114
Main Authors:	Veillon, Lucas, Huang, Yifan, Peng, Wenjing, Dong, Xue, Cho, Byeong Gwan, Mechref, Yehia
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 01.09.2017
Subjects:	carbon chromatography Chromatography, Liquid - methods electrophoresis Glycan Glycan analysis glycomics glycoproteins glycosylation Graphitization ion exchange Isomeric separation Isomerism LC‐MS/MS Linkages Liquid chromatography Mass spectrometry Oligosaccharides polysaccharides Polysaccharides - analysis Polysaccharides - chemistry researchers Tandem Mass Spectrometry - methods Glycan analysis LC-MS/MS Liquid chromatography Mass spectrometry Isomeric separation
ISSN:	0173-0835, 1522-2683, 1522-2683
Online Access:	Get full text
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