Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls

A novel heterozygous non-synonymous mutation and a novel polymorphism in OMI/HTRA2 locus have been associated with Parkinson's disease (PD) in a German population. In an attempt to replicate these results in an independent population, we analyzed the entire coding region of OMI/HTRA2 in a serie...

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Bibliographic Details
Published in:	Human molecular genetics Vol. 17; no. 13; p. 1988
Main Authors:	Simón-Sánchez, Javier, Singleton, Andrew B
Format:	Journal Article
Language:	English
Published:	England 01.07.2008
Subjects:	Adolescent Adult Age of Onset Aged Aged, 80 and over Cohort Studies Female High-Temperature Requirement A Serine Peptidase 2 Humans Male Middle Aged Mitochondrial Proteins - genetics Mutation Parkinson Disease - genetics Polymorphism, Single Nucleotide Sequence Analysis, DNA Serine Endopeptidases - genetics
ISSN:	1460-2083, 1460-2083
Online Access:	Get more information
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