Nervous System Regionalization Entails Axial Allocation before Neural Differentiation

Neural induction in vertebrates generates a CNS that extends the rostral-caudal length of the body. The prevailing view is that neural cells are initially induced with anterior (forebrain) identity; caudalizing signals then convert a proportion to posterior fates (spinal cord). To test this model, w...

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Bibliographic Details
Published in:	Cell Vol. 175; no. 4; p. 1105
Main Authors:	Metzis, Vicki, Steinhauser, Sebastian, Pakanavicius, Edvinas, Gouti, Mina, Stamataki, Despina, Ivanovitch, Kenzo, Watson, Thomas, Rayon, Teresa, Mousavy Gharavy, S Neda, Lovell-Badge, Robin, Luscombe, Nicholas M, Briscoe, James
Format:	Journal Article
Language:	English
Published:	United States 01.11.2018
Subjects:	Animals Cell Line Cells, Cultured Chick Embryo Chromatin Assembly and Disassembly Embryonic Induction Female Gene Expression Regulation, Developmental Male Mice Mice, Inbred C57BL Neural Stem Cells - cytology Neural Stem Cells - metabolism Neurogenesis Spinal Cord - cytology Spinal Cord - growth & development Spinal Cord - metabolism gene regulation CDX embryonic development stem cells and development computational genomics spinal cord chromatin WNT signaling ATAC-seq neural induction
ISSN:	1097-4172, 1097-4172
Online Access:	Get more information
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