The impact of diabetes on the pathogenesis of sepsis

Diabetes is associated with an increased susceptibility to infection and sepsis. Conflicting data exist on whether the mortality of patients with sepsis is influenced by the presence of diabetes, fuelling the ongoing debate on the benefit of tight glucose regulation in patients with sepsis. The main...

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Bibliographic Details
Published in:	European journal of clinical microbiology & infectious diseases Vol. 31; no. 4; pp. 379 - 388
Main Authors:	Koh, G. C. K. W., Peacock, S. J., van der Poll, T., Wiersinga, W. J.
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer-Verlag 01.04.2012 Springer Springer Nature B.V
Subjects:	Bacterial diseases Bacterial sepsis Biological and medical sciences Biomedical and Life Sciences Biomedicine Chemotaxis Data processing Defects Diabetes Diabetes Complications - immunology Diabetes mellitus Diabetes Mellitus - drug therapy Diabetes. Impaired glucose tolerance Disease Susceptibility Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Glucose Hospitals Human bacterial diseases Humans Hypoglycemic Agents - administration & dosage Immune response Immunity, Humoral Infection Infections Infectious diseases Insulin Internal Medicine Intracellular killing Leukocytes (neutrophilic) Medical Microbiology Medical sciences Medicine Metformin Mortality Neutrophils Neutrophils - immunology Pathogenesis Pneumonia Population-based studies Review Sepsis Sepsis - complications Sepsis - mortality thiazolidinediones Tuberculosis Tumor necrosis factor-TNF United Kingdom > UK Metformin Glibenclamide Intensive Insulin Therapy Migration Inhibitory Factor Otitis Externa Endocrinopathy Infection Sepsis syndrome Microbiology Pathogenesis Diabetes mellitus Bacteriosis Bacteremia
ISSN:	0934-9723, 1435-4373, 1435-4373
Online Access:	Get full text
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