Trait impulsivity and impaired prefrontal impulse inhibition function in adolescents with internet gaming addiction revealed by a Go/No-Go fMRI study

Background Recent studies suggest that Internet gaming addiction (IGA) is an impulse disorder, or is at least related to impulse control disorders. In the present study, we hypothesized that different facets of trait impulsivity may be specifically linked to the brain regions with impaired impulse i...

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Published in:Behavioral and brain functions Vol. 10; no. 1; p. 20
Main Authors: Ding, Wei-na, Sun, Jin-hua, Sun, Ya-wen, Chen, Xue, Zhou, Yan, Zhuang, Zhi-guo, Li, Lei, Zhang, Yong, Xu, Jian-rong, Du, Ya-song
Format: Journal Article
Language:English
Published: London BioMed Central 30.05.2014
Springer Nature B.V
Subjects:
Adolescent
Behavior, Addictive - physiopathology
Behavior, Addictive - psychology
Behavioral Therapy
Biomedical and Life Sciences
Biomedicine
Female
Humans
Image Processing, Computer-Assisted
Impulsive Behavior - physiopathology
Impulsive Behavior - psychology
Internet
Magnetic Resonance Imaging
Male
Neurology
Neuropsychological Tests
Neurosciences
Personality - physiology
Prefrontal Cortex - physiopathology
Psychiatry
Surveys and Questionnaires
Video Games
Young Adult
fMRI
Response inhibition
Go/No-Go
Internet addiction
ISSN:1744-9081, 1744-9081
Online Access:Get full text
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Summary:Background Recent studies suggest that Internet gaming addiction (IGA) is an impulse disorder, or is at least related to impulse control disorders. In the present study, we hypothesized that different facets of trait impulsivity may be specifically linked to the brain regions with impaired impulse inhibition function in IGA adolescents. Methods Seventeen adolescents with IGA and seventeen healthy controls were scanned during performance of a response-inhibition Go/No-Go task using a 3.0 T MRI scanner. The Barratt Impulsiveness Scale (BIS)-11 was used to assess impulsivity. Results There were no differences in the behavioral performance on the Go/No-Go task between the groups. However, the IGA group was significantly hyperactive during No-Go trials in the left superior medial frontal gyrus, right anterior cingulate cortex, right superior/middle frontal gyrus, left inferior parietal lobule, left precentral gyrus, and left precuneus and cuneus. Further, the bilateral middle temporal gyrus, bilateral inferior temporal gyrus, and right superior parietal lobule were significantly hypoactive during No-Go trials. Activation of the left superior medial frontal gyrus was positively associated with BIS-11 and Chen Internet Addiction Scale (CIAS) total score across IGA participants. Conclusions Our data suggest that the prefrontal cortex may be involved in the circuit modulating impulsivity, while its impaired function may relate to high impulsivity in adolescents with IGA, which may contribute directly to the Internet addiction process.
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ISSN:1744-9081
1744-9081
DOI:10.1186/1744-9081-10-20