A mitochondrial root to accelerated ageing and frailty

A discovery metabolomic study was performed in a large cohort of adults to identify circulating biomarkers of frailty. The study found that carnitine and vitamin E pathways were dysregulated in frail compared with non-frail participants. These findings point to dysregulated mitochondrial metabolism...

Full description

Bibliographic Details

Published in:	Nature reviews. Endocrinology Vol. 16; no. 3; pp. 133 - 134
Main Authors:	Ferrucci, Luigi, Zampino, Marta
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.03.2020
Subjects:	Aging Biomarkers - metabolism Carnitine Carnitine - metabolism Frailty Humans Metabolomics Mitochondria Mitochondria - metabolism Vitamin E Vitamin E - metabolism
ISSN:	1759-5029, 1759-5037, 1759-5037
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!