Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease

Inflammatory bowel disease (IBD), clinically defined as Crohn’s disease (CD), ulcerative colitis (UC), or IBD-unclassified, results in chronic inflammation of the gastrointestinal tract in genetically susceptible hosts. Pediatric onset IBD represents ≥ 25% of all IBD diagnoses and often presents wit...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Scientific reports Ročník 11; číslo 1; s. 5595 - 10
Hlavní autori:	Horowitz, Julie E., Warner, Neil, Staples, Jeffrey, Crowley, Eileen, Gosalia, Nehal, Murchie, Ryan, Van Hout, Cristopher, Fiedler, Karoline, Welch, Gabriel, King, Alejandra Klauer, Reid, Jeffrey G., Overton, John D., Baras, Aris, Shuldiner, Alan R., Griffiths, Anne, Gottesman, Omri, Muise, Aleixo M., Gonzaga-Jauregui, Claudia
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 10.03.2021 Nature Publishing Group Nature Portfolio
Predmet:	631/208/212/2301 631/208/248 631/208/514 Alleles Crohn's disease Gastrointestinal tract Heredity Humanities and Social Sciences Inflammatory bowel disease Inflammatory bowel diseases Intestine multidisciplinary NOD2 protein Patients Pediatrics Population genetics Science Science (multidisciplinary) Ulcerative colitis
ISSN:	2045-2322, 2045-2322
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!