The genetics and neuropathology of Parkinson’s disease

There has been tremendous progress toward understanding the genetic basis of Parkinson’s disease and related movement disorders. We summarize the genetic, clinical and pathological findings of autosomal dominant disease linked to mutations in SNCA , LRRK2 , ATXN2 , ATXN3 , MAPT, GCH1, DCTN1 and VPS3...

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Veröffentlicht in:	Acta neuropathologica Jg. 124; H. 3; S. 325 - 338
Hauptverfasser:	Houlden, Henry, Singleton, Andrew B.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Berlin/Heidelberg Springer-Verlag 01.09.2012 Springer Springer Nature B.V
Schlagworte:	alpha-Synuclein - genetics Brain - pathology Genetic Predisposition to Disease Genome-Wide Association Study Genomics Humans LRRK2 protein Medicine Medicine & Public Health Movement disorders Mutation Neurodegenerative diseases Neuropathology Neurosciences PARK7 protein Parkinson Disease - genetics Parkinson Disease - pathology Parkinson's disease Pathology PTEN-induced putative kinase Review Reviews Ubiquitin-Protein Ligases - genetics Pathology Genetics Synuclein Parkinson’s disease
ISSN:	0001-6322, 1432-0533, 1432-0533
Online-Zugang:	Volltext
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