A decade of transcription factor-mediated reprogramming to pluripotency

This year marks the tenth anniversary of the generation of induced pluripotent stem cells (iPSCs) by transcription factor-mediated somatic cell reprogramming. Takahashi and Yamanaka portray the path towards this ground-breaking discovery and discuss how, since then, research has focused on understan...

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Veröffentlicht in:	Nature reviews. Molecular cell biology Jg. 17; H. 3; S. 183 - 193
Hauptverfasser:	Takahashi, Kazutoshi, Yamanaka, Shinya
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 01.03.2016 Nature Publishing Group
Schlagworte:	631/136/2444 631/136/532/2435 631/532/2064/2158 Animals Biochemistry Cancer Research Cell Biology Cellular control mechanisms Cellular Reprogramming Cellular Reprogramming Techniques - history Cellular Reprogramming Techniques - methods Developmental Biology Genetic aspects Genetic research Genetic transcription History, 21st Century Humans Innovations Life Sciences Properties Regenerative medicine Stem Cells timeline Transcription factors Transcription Factors - biosynthesis Transcription Factors - genetics
ISSN:	1471-0072, 1471-0080, 1471-0080
Online-Zugang:	Volltext
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