ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

The unfolded protein response (UPR) pathway senses unfolded proteins and regulates proteostasis and cell fate through activity of the transcription factors ATF4, ATF6, and XBP1 within a complex network of three main branches. Here, we investigated contributions of the three branches to UPR activity...

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Bibliographic Details

Published in:	iScience Vol. 23; no. 2; p. 100860
Main Authors:	Yang, Huan, Niemeijer, Marije, van de Water, Bob, Beltman, Joost B.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 21.02.2020 Elsevier
Subjects:	Biocomputational Method Bioinformatics Optical Imaging Systems Biology Optical Imaging Biocomputational Method Bioinformatics Systems Biology
ISSN:	2589-0042, 2589-0042
Online Access:	Get full text
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