ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

The unfolded protein response (UPR) pathway senses unfolded proteins and regulates proteostasis and cell fate through activity of the transcription factors ATF4, ATF6, and XBP1 within a complex network of three main branches. Here, we investigated contributions of the three branches to UPR activity...

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Vydané v:	iScience Ročník 23; číslo 2; s. 100860
Hlavní autori:	Yang, Huan, Niemeijer, Marije, van de Water, Bob, Beltman, Joost B.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Elsevier Inc 21.02.2020 Elsevier
Predmet:	Biocomputational Method Bioinformatics Optical Imaging Systems Biology Optical Imaging Biocomputational Method Bioinformatics Systems Biology
ISSN:	2589-0042, 2589-0042
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