Immunosenescence: what does it mean to health outcomes in older adults?

The most profound consequences of immune senescence with respect to human health are the increased susceptibility to infectious diseases and decreased vaccine efficacy. Changes in both innate and adaptive immune function converge in the reduced response to vaccination and protection against infectio...

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Bibliographic Details
Published in:	Current opinion in immunology Vol. 21; no. 4; pp. 418 - 424
Main Authors:	McElhaney, Janet E, Effros, Rita B
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.08.2009
Subjects:	Adjuvants, Immunologic - therapeutic use Aging - immunology Allergy and Immunology Disease Susceptibility Humans Immune Tolerance - drug effects Immunologic Memory Influenza virus T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes - pathology Treatment Outcome Viral Vaccines - therapeutic use Virus Diseases - immunology Virus Diseases - pathology Virus Diseases - physiopathology Virus Diseases - therapy Viruses - immunology West Nile virus
ISSN:	0952-7915, 1879-0372, 1879-0372
Online Access:	Get full text
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