Serotonin Syndrome Presenting as a Posterior Reversible Encephalopathy Syndrome

Posterior reversible encephalopathy syndrome (PRES) is a neurological syndrome characterized by an altered level of consciousness, headaches, seizure, and visual changes. PRES has several different etiologies, including malignant hypertension, eclampsia, and certain medications. Here, we describe a...

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Bibliographic Details
Published in:Case reports in neurology Vol. 12; no. 1; pp. 63 - 68
Main Authors: Malik, Muhammad Taimur, Majeed, Mohammad Faraz, Zand, Ramin
Format: Journal Article
Language:English
Published: Basel, Switzerland S. Karger AG 01.01.2020
Karger Publishers
Subjects:
adverse reactions
Antibiotics
Antidepressants
Blood pressure
Case reports
cerebral vasoconstriction
Convulsions & seizures
Eclampsia
Emergency medical care
Headaches
Hypertension
Lupus
Magnetic resonance imaging
Pathogenesis
posterior reversible encephalopathy syndrome
Serotonin
serotonin syndrome
Single Case – General Neurology
Single Case − General Neurology
venlafaxine
Venlafaxine
Adverse reactions
Cerebral vasoconstriction
Serotonin syndrome
Posterior reversible encephalopathy syndrome
ISSN:1662-680X, 1662-680X
Online Access:Get full text
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Summary:Posterior reversible encephalopathy syndrome (PRES) is a neurological syndrome characterized by an altered level of consciousness, headaches, seizure, and visual changes. PRES has several different etiologies, including malignant hypertension, eclampsia, and certain medications. Here, we describe a 41-year-old woman who presented with altered mental status. She had a preliminary diagnosis of serotonin syndrome as she was on many different serotonin-sparing agents, but her imaging findings were consistent with PRES. After her medications were reviewed and the causative agent was removed, the patient’s neurological exam and imaging findings improved, and she returned to her baseline. To our knowledge, this is a unique case of PRES caused by serotonin syndrome secondary to venlafaxine usage.
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ISSN:1662-680X
1662-680X
DOI:10.1159/000505907