Gut microbiota mediated the therapeutic efficacies and the side effects of prednisone in the treatment of MRL/lpr mice

Background Growing evidences indicate that the alterations in gut microbiota are associated with the efficacy of glucocorticoids (GCs) in the treatment of systemic lupus erythematosus (SLE). However, there is no evidence to prove whether gut microbiota directly mediates the effects of GCs. Methods U...

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Vydané v:	Arthritis research & therapy Ročník 23; číslo 1; s. 1 - 10
Hlavní autori:	Wang, Mingzhu, Zhu, Zhengyang, Lin, Xiaoying, Li, Haichang, Wen, Chengping, Bao, Jie, He, Zhixing
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BioMed Central 14.09.2021 BioMed Central Ltd Springer Nature B.V BMC
Predmet:	Antibodies Arthritis Care and treatment Corticosteroids Disease Dosage and administration Drug dosages Fecal microbiota transplantation Feces Gut microbiota Health aspects Immunosuppressive agents Laboratory animals Liver Lupus Medical research Medicine Medicine & Public Health Microbiota Microbiota (Symbiotic organisms) MRL/lpr mice Orthopedics Prednisone Research Article Rheumatology Spleen Systemic lupus erythematosus Testing Tumor necrosis factor-TNF China Japan Gut microbiota Prednisone Systemic lupus erythematosus MRL/lpr mice Fecal microbiota transplantation
ISSN:	1478-6362, 1478-6354, 1478-6362
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