Functions of EpCAM in physiological processes and diseases (Review)

EpCAM (epithelial cell adhesion molecule) is a type I transmembrane glycoprotein, which was originally identified as a tumor-associated antigen due to its high expression level in rapidly growing epithelial tumors. Germ line mutations of the human EpCAM gene have been indicated as the cause of conge...

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Bibliographic Details
Published in:	International journal of molecular medicine Vol. 42; no. 4; pp. 1771 - 1785
Main Authors:	Huang, Li, Yang, Yanhong, Yang, Fei, Liu, Shaomin, Zhu, Ziqin, Lei, Zili, Guo, Jiao
Format:	Journal Article
Language:	English
Published:	Greece D.A. Spandidos 01.10.2018 Spandidos Publications Spandidos Publications UK Ltd
Subjects:	Animals cancer Cell adhesion & migration Cell Adhesion - genetics Cell adhesion molecules Cell Movement Cell Proliferation cell-cell junctions congenital tufting enteropathy Disease susceptibility epithelial cell adhesion molecule Epithelial Cell Adhesion Molecule - genetics Epithelial Cell Adhesion Molecule - metabolism Gene expression Genetic aspects Health aspects Humans Medical research Mutation Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neoplasms, Glandular and Epithelial - genetics Neoplasms, Glandular and Epithelial - metabolism Rodents Signal Transduction Small intestine stem cell Zebrafish
ISSN:	1107-3756, 1791-244X, 1791-244X
Online Access:	Get full text
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