Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis

The initial presentation of non-alcoholic steatohepatitis (NASH) is hepatic steatosis. The dysfunction of lipid metabolism within hepatocytes caused by genetic factors, diet, and insulin resistance causes lipid accumulation. Lipotoxicity, oxidative stress, mitochondrial dysfunction, and endoplasmic...

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Bibliographic Details
Published in:	Clinical and molecular hepatology Vol. 29; no. 1; pp. 77 - 98
Main Authors:	Lee, Kuei-Chuan, Wu, Pei-Shan, Lin, Han-Chieh
Format:	Journal Article
Language:	English
Published:	Korea (South) Korean Association for the Study of the Liver 01.01.2023 The Korean Association for the Study of the Liver 대한간학회
Subjects:	Autophagy Body fat Diet Exercise Fatty acids Fatty liver Fibrosis - etiology Humans Inflammation Inflammation - metabolism Inflammation - pathology Insulin Resistance Kinases Lipids Liver - pathology Liver cancer Liver cirrhosis Liver diseases liver fibrosis Metabolism MicroRNAs Non-alcoholic Fatty Liver Disease - drug therapy Non-alcoholic Fatty Liver Disease - pathology Non-alcoholic Fatty Liver Disease - therapy Obesity Overweight Oxidation Oxidative stress Pathogenesis Phosphorylation Proteins Review Sedentary behavior steatohepatitis 내과학 Steatohepatitis Fatty liver Liver fibrosis
ISSN:	2287-2728, 2287-285X, 2287-285X
Online Access:	Get full text
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