Bedaquiline plus delamanid for XDR tuberculosis
The combination was initiated in a patient in whom an effective treatment cannot be designed, in the consideration that its potential life-saving benefits outweigh its unknown adverse event risks; in a department in which more than 100 tuberculosis cases a year are admitted to hospital, of which 14...
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| Vydáno v: | The Lancet infectious diseases Ročník 16; číslo 3; s. 294 |
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| Hlavní autoři: | , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
United States
Elsevier Ltd
01.03.2016
Elsevier Limited |
| Témata: | |
| ISSN: | 1473-3099, 1474-4457, 1474-4457 |
| On-line přístup: | Získat plný text |
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| Shrnutí: | The combination was initiated in a patient in whom an effective treatment cannot be designed, in the consideration that its potential life-saving benefits outweigh its unknown adverse event risks; in a department in which more than 100 tuberculosis cases a year are admitted to hospital, of which 14 cases are multidrug-resistant or XDR disease; after a multisciplinary consultation at the national level; and after patient's informed consent. Conditions for this combination use described by Alberto Matteelli and colleagues2 were therefore fulfilled. [...]this combination was initiated under close cardiac monitoring and was well tolerated over a 6 month period. |
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| Bibliografie: | SourceType-Scholarly Journals-1 ObjectType-Correspondence-1 content type line 14 ObjectType-Commentary-2 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
| ISSN: | 1473-3099 1474-4457 1474-4457 |
| DOI: | 10.1016/S1473-3099(16)00047-5 |